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Clinical Trial Summary

This was a Phase I study in 12 healthy male participants to compare the pharmacokinetic properties of CG5503 (how it is taken up and excreted from the body) after 2 minutes intravenous (i.v.) infusion with and without oral co-administration of charcoal to investigate a potential gastrointestinal secretion of CG5503.

During the course of the study each participant received two infusions of 40 mg CG5503 without (treatment A) and with (treatment B) oral co-administration of charcoal. In treatment B, eight doses of 5 grams charcoal powder were co-administered orally at defined time points. The wash out phases were to be at least 4 to 14 days between the treatment periods.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03951987
Study type Interventional
Source Grünenthal GmbH
Contact
Status Completed
Phase Phase 1
Start date February 2004
Completion date April 2004

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