A Pharmacogenomics Study of Simvastatin-Induced Adverse Drug Reaction

Status Recruiting

Clinical Trial Summary

Adverse reactions of simvastatin are mostly slight and transient, however, the incidence of simvastatin-induced hepatic impairment and myopathy are obviously higher in Chinese population than other racial groups. There is still lack of research data in Chinese. In this study, we will investigate whether there are specific genotypes which may predict the incidence of simvastatin-induced hepatic impairment and myopathy in Chinese so as to provide a basis for developing guidelines on precise medication in simvastatin therapy apply to Chinese population.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Accurate Medication
Drug-Related Side Effects and Adverse Reactions
Pharmacogenomics
Simvastatin Adverse Reaction

Clinical Trial Details

NCT number	NCT03261908
Study type	Observational
Source	Peking University First Hospital
Contact	Qian Xiang, Ph.D
Phone	+86 010 66110802
Email	xiangqz@126.com
Status	Recruiting
Phase
Start date	August 2018
Completion date	December 2018

View Details

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