Comparison of Salivary pH After Consuming Milk of Origin Vegetable vs Cow's Milk in Children

pH Clinical Trial

Official title:

Comparison of Salivary pH After Consuming Milk of Origin Vegetable vs Cow's Milk in Children

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04717778
• Other study ID #: 2019-100
• Status: Completed
• Phase: N/A
• Start date: January 13, 2020
• Est. completion date: January 17, 2020

Study information

• Verified date: January 2021
• Source: Universidad Tecnologica de Mexico
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The study was carried out in 21 first grade primary school children, 100% aged 6 years, 52.4% were female. They were given 5 types of milk, each one was measured on different days (Monday cow's milk, Tuesday coconut milk, Wednesday almond milk, Thursday soy milk, Friday rice milk)

Description:

• The study was carried out in 21 first grade primary school children, 100% aged 6 years, 52.4% were female.

• The group was given a brushing technique using a model and 2 videos were shown to reinforce the brushing technique and explanation of what was going to be done in the study.

• Supervised tooth brushing was performed in a group of 5 people.

• They were given 5 types of milk, each one was measured on different days (Monday cow's milk, Tuesday coconut milk, Wednesday almond milk, Thursday soy milk, Friday rice milk).

• Each child was given 7 plastic cups each day and asked to pour their saliva into the cup when instructed.

• The samples were taken with pH indicator strips and the result was recorded in personalized tables.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 21
• Est. completion date: January 17, 2020
• Est. primary completion date: January 17, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 3 Years to 6 Years

Eligibility

Inclusion Criteria:

• Boys and girls from 3 to 6 years

Exclusion Criteria

• Boys and girls with allergies

• Children with lactose intolerance

Elimination criteria:

• Boys and girls who do not want to participate at the time of the study

Related Conditions & MeSH terms

• pH

Intervention

Dietary Supplement:
• Comparison of salivary pH after consuming milk of origin vegetable vs cow's milk
They were given 5 types of milk, each one was measured on different days (Monday cow's milk, Tuesday coconut milk, Wednesday almond milk, Thursday soy milk, Friday rice milk).

Locations

Country	Name	City	State
Mexico	UNITEC	Mexico City

Sponsors (1)

Lead Sponsor	Collaborator
Universidad Tecnologica de Mexico

Country where clinical trial is conducted

Mexico, 

References & Publications (3)

Cuppari C, Manti S, Salpietro A, Dugo G, Gitto E, Arrigo T, Sturiale M, Salpietro C. ALMOND MILK: A POTENTIAL THERAPEUTIC WEAPON AGAINST COW'S MILK PROTEIN ALLERGY. J Biol Regul Homeost Agents. 2015 Apr-Jun;29(2 Suppl 1):8-12. — View Citation

Hettinga K, van Valenberg H, de Vries S, Boeren S, van Hooijdonk T, van Arendonk J, Vervoort J. The host defense proteome of human and bovine milk. PLoS One. 2011 Apr 27;6(4):e19433. doi: 10.1371/journal.pone.0019433. — View Citation

Vanga SK, Raghavan V. How well do plant based alternatives fare nutritionally compared to cow's milk? J Food Sci Technol. 2018 Jan;55(1):10-20. doi: 10.1007/s13197-017-2915-y. Epub 2017 Nov 2. Review. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Sociodemographic results	The study was carried out in 21 first grade primary school children, 100% aged 6 years, 52.4% were female.	1 hour the sociodemographic data of all the children were taken.
Primary	pH results	30 minutes after tooth brushing, each child was asked for the first saliva sample (basal pH measurement).; After taking the basal pH, each child was given a glass with 50 ml of the milk to be measured.; Saliva samples were measured with pH indicator strips and the result was recorded on custom charts.; The pH was taken at 5, 10, 20, 30, 40 and 50 minutes.; The normality distribution test (Shapiro-Wilk) was applied to the quantitative variables, with p = 0.0001, so that the data present a non-parametric or free distribution.; To assess whether there were differences between the pH of the groups, the Kuskal-Wallis test was applied. For basal pH, p = 0.0001, therefore the null hypothesis is rejected and we conclude that the basal pH level is different in the five milks. Average basal pH: Rice milk 7 Cow milk 6.9 Almond milk 6.6 Soy milk 6.4 Coconut milk 6	The average time of pH evaluation for each milk per child was an hour and a half.