Peritoneal Dialysis Daily Versus Six Days Per Week

Peritoneal Dialysis Clinical Trial

Official title:

Peritoneal Dialysis Daily Versus Six Days Per Week

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06399848
• Other study ID #: 75365
• Status: Not yet recruiting
• Phase: N/A
• Start date: July 2024
• Est. completion date: June 2025

Study information

• Verified date: May 2024
• Source: Stanford University
• Contact: Timothy W Meyer, MD
• Phone: 650-852-3314
• Email: twmeyer[@]stanford.edu
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The study will enroll patients receiving daily peritoneal dialysis who have significant residual native kidney function. The investiators will visit the patients at a routinely scheduled clinic visit and again at a non-routine visit after the patients skip a single day of dialysis. Blood samples will be obtained and a quality of life questionnaire will be administered at both visits.

The primary aim will be to determine whether the patients would prefer daily treatment or being allowed to skip one day per week.

Other aims will be to determine the effect of skipping a day on plasma levels of urea nitrogen and creatinine.

Description:

The patients' preference will be assessed by asking the simple question would you prefer to perform peritoneal dialysis daily of six days per week.

The quality of life questionnaire to be used will be the Dialysis Symptom Index (DSI) which has a range of 0 to 150 with a high score reflecting worse quality of life.

The chemical to be measured will be the plasma urea nitrogen in mg/dl and the plasma creatinine in mg/dl as measured by the clinical laboratory.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 20
• Est. completion date: June 2025
• Est. primary completion date: June 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Daily treament with peritoneal dialysis and residual native kidney funciton with residual urea clearance greater than 2 ml/min.

Exclusion Criteria:

• less than 3 months on peritoneal dialysis

• recent change in the dialysis prescriptoin

• recent peritonitis

Related Conditions & MeSH terms

• Peritoneal Dialysis

Intervention

Other:
• Skip one day of peritoneal dialysis treatment
Skip one day of peritoneal dialysis treatment

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Stanford University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Patient's preference for treatment regimen	Patient's stated preference for dialysis daily versus six days per week	Two weeks per patient
Secondary	Symptoms	Quality of Life as assessed by a questionnaire	Two weeks per patient
Secondary	Plasma solute levels	Plasma levels of urea nitrogen and creatinine.	Two weeks per patient