Alpha-lipoic Acid in Patients at Risk for Paclitaxel Induced Neuropathy

Status Completed

Clinical Trial Summary

This study is being done because peripheral neuropathy, a condition that interrupts sensation in your limbs, is a common side effect of paclitaxel. There is some evidence that alpha lipoic acid (ALA), an antioxidant compound, protects neurons after exposure to paclitaxel. The purpose of this study is to assess the safety and tolerability of ALA and to find the best dose of ALA in patients that receive chemotherapy.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Peripheral Nervous System Diseases
Peripheral Neuropathy

Clinical Trial Details

NCT number	NCT01313117
Study type	Interventional
Source	Northwestern University
Contact
Status	Completed
Phase	Phase 1/Phase 2
Start date	February 2012
Completion date	January 2014

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