Peripheral Muscle Strength Clinical Trial
Official title:
Clinical Determinants of Handgrip Strength in Critically Ill Adults: Pilot Study
To better understand ICU-acquired weakness in patients requiring mechanical ventilation in the Intensive Care Unit.
We have generated the hypothesis that handgrip strength can be used to develop our
understanding of the effects of critical illness on peripheral muscle strength.
To begin to develop this hypothesis, a better understanding of the determinants of handgrip
strength needs to be developed. As a result we propose to perform a prospective
observational study examining the clinical factors that are associated with handgrip
strength. Several clinical factors are known to be associated with increased risk of
developing ICUAP while hospitalized: multiple organ failure, severe sepsis, female gender
and treatments like steroids. As many of these risk factors are not modifiable, the
opportunity to intervene is unclear. However, by attempting to better describe the spectrum
of strength deficits experienced by critically ill patients we may better be able to dissect
and prevent ICUAP.
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Observational Model: Case-Only, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Enrolling by invitation |
NCT05665673 -
Relation of Functional ındependence to Balance, Exercise Capacity, and Peripheral Muscle Strength
|