Peripheral Arterial Disease Clinical Trial
— PREPAREDOfficial title:
Predicting Peripheral Arterial Disease in Men With Erectile Dysfunction
Verified date | September 2008 |
Source | Bruton Avenue Family Practice |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Institutional Review Board |
Study type | Observational |
Erectile dysfunction is a common complaint and is found frequently in men with hyperlipidemia, hypertension, diabetes and those who smoke. ED may also be an early warning of peripheral arterial disease. This study is designed to look for a relationship between the degree of ED and the presence of PAD when associated with co-morbid conditions.
Status | Completed |
Enrollment | 175 |
Est. completion date | May 2008 |
Est. primary completion date | February 2008 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 50 Years and older |
Eligibility |
Inclusion Criteria: - Men 50 years old or older - Must have a history of diabetes, hypertension, hyperlipidemia and/or a history of tobacco use Exclusion Criteria: - Men younger than 50 years of age - No co-morbid condition such as diabetes, hypertension, hyperlipidemia and/or tobacco use. |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
United States | UMass, Fitchburg Family Medicine Center | Fitchburg | Massachusetts |
United States | Mercury West Family Practice | Hampton | Virginia |
United States | Bruton Avenue Family Practice | Newport News | Virginia |
United States | Hilton Family Practice | Newport News | Virginia |
United States | Williamsburg Medical Arts-Family Medicine | Williamsburg | Virginia |
Lead Sponsor | Collaborator |
---|---|
Bruton Avenue Family Practice | Pfizer |
United States,
Brunton S: Raising the Profile of Peripheral Arterial Disease. AANP 18th Annual National Conference, July 1, 2003, Anaheim, CA.
Cappelleri JC, Rosen RC. The Sexual Health Inventory for Men (SHIM): a 5-year review of research and clinical experience. Int J Impot Res. 2005 Jul-Aug;17(4):307-19. Review. — View Citation
Carman TL, Fernandez BB Jr. A primary care approach to the patient with claudication. Am Fam Physician. 2000 Feb 15;61(4):1027-32, 1034. Review. — View Citation
Champion H. Erectile Dysfunction and Cardiovascular Disease: Carrots, Sticks, and Better Men's Health. Adv Stud Med. 6(4):163-170, 2006
Deedwania PC. Endothelium: a new target for cardiovascular therapeutics. J Am Coll Cardiol. 2000 Jan;35(1):67-70. — View Citation
Fedele D, Bortolotti A, Coscelli C, Santeusanio F, Chatenoud L, Colli E, Lavezzari M, Landoni M, Parazzini F. Erectile dysfunction in type 1 and type 2 diabetics in Italy. On behalf of Gruppo Italiano Studio Deficit Erettile nei Diabetici. Int J Epidemiol — View Citation
Gazzaruso C, Giordanetti S, De Amici E, Bertone G, Falcone C, Geroldi D, Fratino P, Solerte SB, Garzaniti A. Relationship between erectile dysfunction and silent myocardial ischemia in apparently uncomplicated type 2 diabetic patients. Circulation. 2004 J — View Citation
Grover SA, Lowensteyn I, Kaouache M, Marchand S, Coupal L, DeCarolis E, Zoccoli J, Defoy I. The prevalence of erectile dysfunction in the primary care setting: importance of risk factors for diabetes and vascular disease. Arch Intern Med. 2006 Jan 23;166( — View Citation
Hirsch AT, Criqui MH, Treat-Jacobson D, Regensteiner JG, Creager MA, Olin JW, Krook SH, Hunninghake DB, Comerota AJ, Walsh ME, McDermott MM, Hiatt WR. Peripheral arterial disease detection, awareness, and treatment in primary care. JAMA. 2001 Sep 19;286(1 — View Citation
Hurairah H, Ferro A. The role of the endothelium in the control of vascular function. Int J Clin Pract. 2004 Feb;58(2):173-83. Review. — View Citation
Jackson G. Endothelial function and dysfunction. Int J Clin Pract. 2004 May;58(5):431. — View Citation
Kloner RA. Erectile dysfunction in the cardiac patient. Curr Urol Rep. 2003 Dec;4(6):466-71. Review. — View Citation
Lue TF. Erectile dysfunction. N Engl J Med. 2000 Jun 15;342(24):1802-13. Review. — View Citation
Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A. The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology. 1997 Jun;49(6):822-30. — View Citation
Solomon H, Man JW, Jackson G. Erectile dysfunction and the cardiovascular patient: endothelial dysfunction is the common denominator. Heart. 2003 Mar;89(3):251-3. Review. — View Citation
Sutton-Tyrrell K, Rihal C, Sellers MA, Burek K, Trudel J, Roubin G, Brooks MM, Grogan M, Sopko G, Keller N, Jandová R. Long-term prognostic value of clinically evident noncoronary vascular disease in patients undergoing coronary revascularization in the B — View Citation
Vinick A, Richardson D. Erectile Dysfunction in Diabetes. Diabetic Reviews 6:16-33, 1998.
* Note: There are 17 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Sexual Health Inventory for Men (SHIM) | initial visit | No | |
Secondary | Ankle-Brachial Index (ABI) | Initial Visit | No |
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