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Protocol-based Management and Perioperative Outcomes in Patients With Chronic Antithrombotic Therapy

Perioperative Care Clinical Trial

Official title:
Effect of Protocol-based Management on Perioperative Outcomes in Patients With Chronic Antithrombotic Therapy: a Pragmatic Interventional Study

Clinical Trial Summary

The purpose of this pragmatic interventional study is to evaluate whether a protocol-based management of antithrombotic drugs can reduce a composite of perioperative outcomes in patients with chronic antithrombotic therapy before surgery.

Clinical Trial Description

Aging population and chronic medical disease make the management of surgical patients more complex. About one tenth of patients scheduled for surgery are taking antithrombotic medications. Coagulation disturbance induced by these medications may increase the risk of bleeding, whereas withholding these medications may increase the risk of thrombotic events. It is a dilemma when managing these patients. The guidelines and expert consensus published by multiple disciplinary teams constitute the perioperative antithrombotic management protocols. However, the effects of perioperative antithrombotic management guided by these guidelines or expert consensus are seldom reported. The investigators hypothesize that a protocol-based perioperative antithrombotic management can benefit patients with chronic antithrombotic therapy before surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04852406
Study type Interventional
Source Peking University First Hospital
Contact Hong Zhang, MD
Phone 86 10 83572784
Email zhanghong40@hotmail.com
Status Recruiting
Phase N/A
Start date April 21, 2021
Completion date January 2024
View Details
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