NCT03816930 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Ahmed SN, Donovan TE
Gingival displacement: Survey results of dentists' practice procedures. J Prosthet Dent. 2015 Jul;114(1):81-5.e1-2. doi: 10.1016/j.prosdent.2014.11.015. Epub 2015 Apr 24.
Al-Ani A, Bennani V, Chandler NP, Lyons KM, Thomson WM
New Zealand dentists' use of gingival retraction techniques for fixed prosthodontics and implants. N Z Dent J. 2010 Sep;106(3):92-6.
de Gennaro GG, Landesman HM, Calhoun JE, Martinoff JT
A comparison of gingival inflammation related to retraction cords. J Prosthet Dent. 1982 Apr;47(4):384-6.
Ferrari M, Cagidiaco MC, Ercoli C
Tissue management with a new gingival retraction material: a preliminary clinical report. J Prosthet Dent. 1996 Mar;75(3):242-7.
Goldberg PV, Higginbottom FL, Wilson TG
Periodontal considerations in restorative and implant therapy. Periodontol 2000. 2001;25:100-9. Review.
Kopac I, Cvetko E, Marion L
Gingival inflammatory response induced by chemical retraction agents in beagle dogs. Int J Prosthodont. 2002 Jan-Feb;15(1):14-9.
Padbury A Jr, Eber R, Wang HL
Interactions between the gingiva and the margin of restorations. J Clin Periodontol. 2003 May;30(5):379-85. Review.
Polat NT, Ozdemir AK, Turgut M
Effects of gingival retraction materials on gingival blood flow. Int J Prosthodont. 2007 Jan-Feb;20(1):57-62.

Evaluation of Gingival Health Parameters in Hybrid CAD / CAM Crowns Produced After Different Retraction Processes

Clinical trial NCT03816930 - References