Guided Tissue Regeneration in Healing of Through and Through Periapical Lesion

Periapical Lesion Clinical Trial

Official title: Healing Following Use Of Injectable Platelet Rich Fibrin With Collagen During Surgery In Through And Through Periapical Lesions

Status Recruiting

Clinical Trial Summary

Aim of this study is to evaluate the effect of i-PRF in the healing of through and through periapical lesion after periradicular surgery

Clinical Trial Description

Detailed patient examination will be carried out and those satisfying inclusion criteria will be enrolled in the study. Written informed consent will be obtained and patients will be randomly allocated to two groups. Entire surgical procedure will be carried out by single operator. After complete elevation of the flap, debridement (periradicular curettage -enucleation) of the bony lesion will be performed. 3 mm root-tip resection will be performed and root end cavity will be prepared using an ultrasonic diamond-coated retrotip. Root end filling will be done with mineral trioxide aggregate (MTA). In test group The i-PRF will be produced and incorporated with collagen will be used to fill into the defect. In the control group, no guided tissue regeneration technique will be used. Flap will be re-positioned and sutured using nonabsorbable 4-0 silk sutures.Sutures will be removed 4-7 days postoperatively. ;

Related Conditions & MeSH terms

• Periapical Lesion

• NCT number: NCT04391725
• Study type: Interventional
• Source: Postgraduate Institute of Dental Sciences Rohtak
• Status: Recruiting
• Phase: N/A
• Start date: December 11, 2019
• Completion date: April 11, 2021