Periapical Diseases Clinical Trial
Official title:
The Accuracy of Magnetic Resonance Imaging in Diagnosing Endodontic Periapical Lesion
The radiolucent periapical jaw lesions of 34 patients, which were surgically enucleated, were
investigated by two radiologists using MRI, based on the same six criteria, to categorize the
lesions as granulomas or radicular cysts. After apicoectomies, two oral pathologists (blinded
to the radiologist's diagnoses) analyzed all specimens by referring to seven specific
parameters and diagnosed the specimens as granulomas or radicular cysts. The inter-rater
agreements between the radiologists and pathologists in terms of MRI and histological
diagnoses, respectively, along with the discriminant power of the adopted criteria and the
accuracy of the MRI assessments compared with the histopathologic results, were calculated.
A strong inter-rater reliability was observed between the two radiologists (k-statistic =
0.86, p = 0.0001) and the two pathologists (k-statistic = 0.88, p = 0.0001). Reliability was
higher for the radiological (Guttmann's lambda lower bound > 0.6) than histopathological
criteria. The accuracy (true positives plus true negatives) of the radiologists was higher
than that of the pathologists based on receiver operator characteristic analysis (area under
the curve = 0.87 and 0.91, respectively). MRI reliability and accuracy were high and
comparable to histopathological reliability, highlighting the usefulness of this non-invasive
exam as a pre-treatment diagnostic method for periapical endodontic lesions.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02625298 -
Use of Mineral Trioxide Aggregate in the Treatment of Traumatized Teeth
|
Phase 2 | |
| Recruiting |
NCT05888935 -
Detection of Periapical Lesions on Dental Panoramic Radiographs Based on Artificial Intelligence
|
||
| Completed |
NCT05555563 -
Effect of MTAD on The Outcome of Primary Root Canal Treatment
|
N/A | |
| Active, not recruiting |
NCT05555043 -
Comparison of Clinical Outcomes Between GentleWave® and Biolase®
|
N/A | |
| Enrolling by invitation |
NCT05714384 -
Outcome of Calcium Silicate Sealer-based Obturation in Root Canal Retreatment
|
||
| Not yet recruiting |
NCT05305417 -
Cell-free Autologous Regenerative Endodontics Treatment for Teeth With Periapical Lesions (CARETT)
|
N/A | |
| Completed |
NCT03108183 -
Apicoectomy Longterm Results
|
N/A | |
| Active, not recruiting |
NCT02196740 -
Research of the Application of Triple Antibiotic Paste in Primary Teeth With Pericpical Periodontitis
|
N/A | |
| Completed |
NCT04311879 -
Efficiency of Soft Tissue Diode Laser Application on Healing of Periapical Tissues
|
N/A | |
| Completed |
NCT04315259 -
Efficiency of Diode Laser in Control of Post-endodontic Pain
|
N/A | |
| Completed |
NCT04311905 -
Efficiency of Diode Laser Activated Irrigation on Healing of Periapical Tissues
|
N/A | |
| Completed |
NCT06250114 -
Retreat or Replace: Retrospective Investigation on a Cohort of Local Patients
|
||
| Recruiting |
NCT06258798 -
The Use of Artificial Intelligence in the Dental X-rays Analysis
|
||
| Recruiting |
NCT06252337 -
Survival and Success of Two Different Filling Techniques
|
N/A | |
| Active, not recruiting |
NCT05478811 -
Evaluation of RANKL/OPG Levels in Gingival Crevicular Fluid at 1st and 3rd Months of Activation of NaOCl With Er,Cr YSSG Laser in Root Canal Treatment
|
N/A | |
| Completed |
NCT05863728 -
Post-Operative Evaluation of Endodontic Microsurgeries Done Using a Piezoelectric Ultrasonic Technique: An in Vivo Study
|
N/A | |
| Completed |
NCT05943769 -
The Impact of Root End Filling Material Type and the Application of Bone Graft on Healing of Periapical Tissues After Endodontic Microsurgery (A Clinical Randomized Controlled Trial)
|
N/A | |
| Completed |
NCT04333940 -
Impact of Periapical Radiography and Cone Beam Computed Tomography on Periapical Assessment Following Surgical Endodontic Treatment
|
N/A | |
| Completed |
NCT04348578 -
Effect of QMix 2in1 as Final Irrigation Protocol on Periapical Healing
|
N/A | |
| Not yet recruiting |
NCT06035185 -
Microbial Load After Apical Enlargement in Asymptomatic Teeth With Periapical Lesion
|