Periapical Diseases Clinical Trial
Official title:
Use of Mineral Trioxide Aggregate in the Treatment of Traumatized Permanent Teeth With Necrotic Pulps and Chronic Periapical Lesions
Verified date | July 2017 |
Source | Association of Paediatric and Preventive Dentists of Serbia |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Traumatic tooth injuries are common in children and adolescents, and often result in pulpal necrosis and the development of periapical lesions. Treatment of traumatized teeth with endodontic complications depends on the type of injury, number of injured teeth, root development and patient cooperation, which altogether will create a challenge and dictate the treatment plan for the dentist. The purpose of this study was to assess the effectiveness of non-surgical root canal procedures in traumatized permanent teeth with necrotic pulps and chronic periapical lesions using a tri-antibiotic paste and calcium-hydroxide as intracanal medications and two different mineral trioxide aggregate (MTA) products for definitive obturation.
Status | Completed |
Enrollment | 24 |
Est. completion date | March 2016 |
Est. primary completion date | December 2015 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 7 Years to 18 Years |
Eligibility |
Inclusion Criteria: - Healthy patient - Non-vital tooth with chronic periapical lesions - Restorable tooth - No horizontal or vertical root fractures - No root resorption Exclusion Criteria: - Unrestorable tooth - Horizontal or vertical root fractures - Root resorption |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Association of Paediatric and Preventive Dentists of Serbia |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Changes Between Initial and Post Treatment Dimensions of Periapical Lesions | Changes in the dimensions of periapical lesions will be performed according to the analysis of initial and post treatment radiographs (baseline, 3, 6, 12, and 24-months subsequent to obturation) after being photographed using a digital camera Kodak EasyShare Max (Z990) with millimetre measurer in order to obtain interpretation of sizes of periapical lesions during conversion of pixels in mm2 by digital data processing in Adobe Photoshop CS software. Sucessful radiographic assessment will include decrease in size of the periapical lesion at the recall time of 24 months. | baseline, 3, 6, 12 and 24 months | |
Secondary | Presence of Clinical Symptoms | Clinical examination will be used to assess the presence of spontaneous or provoked pain, discomfort during chewing, numbness or tenderness to percussion and/or palpation, altered tooth mobility, tooth crown discoloration or abscess and/or sinus tract. | baseline |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05888935 -
Detection of Periapical Lesions on Dental Panoramic Radiographs Based on Artificial Intelligence
|
||
Completed |
NCT05555563 -
Effect of MTAD on The Outcome of Primary Root Canal Treatment
|
N/A | |
Active, not recruiting |
NCT05555043 -
Comparison of Clinical Outcomes Between GentleWave® and Biolase®
|
N/A | |
Enrolling by invitation |
NCT05714384 -
Outcome of Calcium Silicate Sealer-based Obturation in Root Canal Retreatment
|
||
Not yet recruiting |
NCT05305417 -
Cell-free Autologous Regenerative Endodontics Treatment for Teeth With Periapical Lesions (CARETT)
|
N/A | |
Completed |
NCT03108183 -
Apicoectomy Longterm Results
|
N/A | |
Active, not recruiting |
NCT02196740 -
Research of the Application of Triple Antibiotic Paste in Primary Teeth With Pericpical Periodontitis
|
N/A | |
Completed |
NCT04315259 -
Efficiency of Diode Laser in Control of Post-endodontic Pain
|
N/A | |
Completed |
NCT04311879 -
Efficiency of Soft Tissue Diode Laser Application on Healing of Periapical Tissues
|
N/A | |
Completed |
NCT04311905 -
Efficiency of Diode Laser Activated Irrigation on Healing of Periapical Tissues
|
N/A | |
Completed |
NCT06250114 -
Retreat or Replace: Retrospective Investigation on a Cohort of Local Patients
|
||
Recruiting |
NCT06258798 -
The Use of Artificial Intelligence in the Dental X-rays Analysis
|
||
Recruiting |
NCT06252337 -
Survival and Success of Two Different Filling Techniques
|
N/A | |
Active, not recruiting |
NCT05478811 -
Evaluation of RANKL/OPG Levels in Gingival Crevicular Fluid at 1st and 3rd Months of Activation of NaOCl With Er,Cr YSSG Laser in Root Canal Treatment
|
N/A | |
Completed |
NCT05863728 -
Post-Operative Evaluation of Endodontic Microsurgeries Done Using a Piezoelectric Ultrasonic Technique: An in Vivo Study
|
N/A | |
Completed |
NCT05943769 -
The Impact of Root End Filling Material Type and the Application of Bone Graft on Healing of Periapical Tissues After Endodontic Microsurgery (A Clinical Randomized Controlled Trial)
|
N/A | |
Completed |
NCT04333940 -
Impact of Periapical Radiography and Cone Beam Computed Tomography on Periapical Assessment Following Surgical Endodontic Treatment
|
N/A | |
Completed |
NCT03227172 -
Differential Diagnosis Between Granuloma and Radicular Cyst: Effectiveness of Magnetic Resonance Imaging.
|
N/A | |
Completed |
NCT04348578 -
Effect of QMix 2in1 as Final Irrigation Protocol on Periapical Healing
|
N/A | |
Not yet recruiting |
NCT06035185 -
Microbial Load After Apical Enlargement in Asymptomatic Teeth With Periapical Lesion
|