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Effect of Probiotic Lactobacillus Reuteri in the Treatment of Mucositis and Periimplantitis

Peri-implantitis Clinical Trial

Official title:
Clinical and Microbiological Evaluation of the Effect of Probiotic Lactobacillus Reuteri Prodentis in the Treatment of Mucositis and Periimplantitis

Clinical Trial Summary

Evaluate clinically and microbiologically the effect of the oral probiotic Lactobacillus reuteri Prodentis (PerioBalance®, Sunstar, Switzerland) on implants with mucositis or periimplantitis, as a coadjuvant treatment of mechanical therapy.

Clinical Trial Description

A total of 44 patients, 22 with mucositis and 22 with periimplantitis, were randomly assigned to either the control or the test group, so that 11 patients received placebo and 11 probiotic treatment. After the baseline clinical, radiological and microbiological examination, and once the study group was randomly assigned (probiotic or placebo), supragingival prophylaxis was performed in the mucositis group and subgingival mechanical therapy in the periimplantitis group. Then they get a container with 30 probiotic or placebo tablets and instructions on how and when to take them. At 30 and 90 days after beginning the treatment, a clinical, radiological and microbiological examination was performed. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03047291
Study type Interventional
Source Universitat Internacional de Catalunya
Contact
Status Completed
Phase Phase 4
Start date January 1, 2014
Completion date September 1, 2017
View Details
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