PPG vs. ICG in Gastrointestinal Resections

Perfusion Clinical Trial

Official title: Comparison Between Fluorescenceimaging With Photoplethysmography （PPG） and Indocyaningreen (ICG) for Tissue Perfusion in Gastrointestinal Resections

Status Recruiting

Clinical Trial Summary

In this study, gastrointestinal anastomoses are examined with imaging Photoplethysmography and after this the investigators use the Standard Routine ICG-Imaging. At the end, both methods will be compared.

Clinical Trial Description

All gastrointestinal anastomoses were examined in all patients with written informed consent.

As Standard in our clinical Routine the tissue perfusion is measured with fluorescence Imaging and Indocyaningreen (ICG). In this study the investigators use the Imaging photoplethysmography (iPPG) as new method.IPPG is an optical technique in which a conventional video camera is used to detect tiny modulations associated with blood pulsation in vessels.This technique is contactless, extremely simple, and does not affect hemodynamic processes in living organs. It is an emerging technique that allows to sense cardiovascular signals in the outer skin layers.Various research groups recently applied iPPG to monitor the vascular changes (dilatation or vasoconstriction) caused by functional tests.These experiments suggest that the normalized amplitude of the photoplethysmography (PPG) waveform can be considered as a perfusion index. More recently, our group has demonstrated the feasibility of using iPPG to assess changes in cortical blood flow in open brain neurosurgery and tissue perfusion during abdominal surgery.

As Standard method ICG-Fluorescence Imaging is used. After the procedure the Perfusion data of both Systems is compared. ;

Related Conditions & MeSH terms

• Anastomosis
• Perfusion

• NCT number: NCT06222645
• Study type: Interventional
• Source: Saint Petersburg State University, Russia
• Contact: Xuan Qiu, MD
• Phone: 79643411524
• Email: st122986@student.spbu.ru
• Status: Recruiting
• Phase: N/A
• Start date: November 1, 2023
• Completion date: February 28, 2026