Serum Zinc, Peptic Ulcer Disease and H. Pylori Infection

Peptic Ulcer Disease Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02716025
• Other study ID #: 811
• Status: Completed
• Phase: N/A
• First received: March 17, 2016
• Last updated: March 21, 2016
• Start date: October 2013
• Est. completion date: August 2015

Study information

• Verified date: March 2016
• Source: Ain Shams University
• Contact: n/a
• Is FDA regulated: No
• Health authority: Egypt: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

Fifty consecutive patients with symptoms suggestive of peptic ulcer disease were included. All underwent complete clinical evaluation, laboratory investigations, upper gastrointestinal endoscopy and rapid urease test. Measurement of serum zinc level was done for all the included patients in addition to twenty five age and sex matched healthy control subjects.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 75
• Est. completion date: August 2015
• Est. primary completion date: August 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 55 Years

Eligibility

Inclusion Criteria:

• Symptoms suggestive of peptic ulcer disease like epigastric pain, dyspepsia, heartburn

Exclusion Criteria:

• Patients who received zinc supplementation, proton pump inhibitors (PPI), non-steroidal anti-inflammatory drugs (NSAIDs)

• Those presented with hematemesis or melena

• Those with chronic liver disease, renal failure, malabsorption or previous gastric surgery

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Peptic Ulcer
• Peptic Ulcer Disease

Intervention

Procedure:
• Upper gastrointestinal endoscopy
Thorough examination of the esophagus, stomach and duodenum to the second part was done to all patients using Olympus CV-150 or Pentax EPM-3500.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Ain Shams University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Detection of positive upper GIT endoscopic findings		upon endoscopy	Yes