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Alterations in Connective Tissue in Patients With or Without Pelvic Organ Prolapse

Pelvic Organ Prolapse Clinical Trial

Official title:
Alterations in Connective Tissue in Patients With or Without Pelvic Organ Prolapse.

Clinical Trial Summary

The aim of our study is to investigate the alterations in connective tissue of vaginal wall in patients with and without pelvic organ prolapse (POP).

Clinical Trial Description

The tissue samples were taken from the anterior wall of vagina in the midline close to cervix or apex. The tissue samples were collected from the vaginal wall of the patients with pelvic organ prolapse (n=39) during vaginal prolapse surgery. Control samples (n=39) were taken from patients after vaginal or laparoscopic removal of the uterus.

The formalin-fixed and paraffin embedded tissue samples were stained with Verhoeff van Gieson and Movat's pentachrome. Samples were examined by pathologist and gynecologist blinded as to the other investigator and to the pelvic organ prolapse status. In case of discrepancy investigators evaluated the samples together to gain consensus. ;

Study Design

N/A

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01749696
Study type Observational
Source Turku University Hospital
Contact
Status Completed
Phase N/A
Start date November 2009
Completion date April 2014
View Details
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