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Pelvic Organ Prolapse clinical trials

View clinical trials related to Pelvic Organ Prolapse.

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NCT ID: NCT06263985 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

Axis(TM) Solvent-dehydrate Dermal Allograft in the Treatment of Pelvic Organ Prolapse.

Start date: November 2, 2021
Phase: Phase 4
Study type: Interventional

The goal of this study is to assess improvement in subjects who have undergone Axis Dermis, biologic mesh for pelvic organ prolapse repair. [describe participant population/health conditions]. The main question[s] it aims to answer are: - Is the leading edge of the prolapse above the hymen - Does subject notice a bulge Participants will undergo Axis Dermis pelvic organ prolapse repair procedure.

NCT ID: NCT06225375 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

Flat Polypropylene Mesh in the Treatment of Uterine and Recurrent or Advanced Pelvic Organ Prolapse

Start date: September 1, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

This study is being done to evaluate the safety and feasibility of using flat polypropylene Restorelle® mesh, an ultra-lightweight mesh, for transvaginal use in surgically correcting certain specific cases of pelvic organ prolapse, such as recurrent (previous failed native tissue repair), large stage III or IV pelvic organ prolapse, and those with symptomatic uterine prolapse desiring uterine-sparing surgery (called hysteropexy).

NCT ID: NCT06128291 Active, not recruiting - Prolapse; Female Clinical Trials

Concomitant Posterior Colporrhaphy on Bowel Functions in Pelvic Organ Prolapse Repair

Start date: March 3, 2023
Phase:
Study type: Observational

Compare the changes of preoperative and postoperative posterior colporrhaphy.

NCT ID: NCT05969067 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

Retroperitoneal Tunneling Versus Dissection Technique During Sacrocolpopexy

Start date: August 10, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to compare operative time, patient reported outcomes, surgical complications, and surgical outcomes between the tunneling versus dissection technique during robotic assisted sacrocolpopexy (RA SCP).

NCT ID: NCT05422209 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

The Influence of Simultaneous Posterior Colporrhaphy and Perineoplasty on the Efficiency and Safety of Mesh-augmented Sacrospinal Fixation (Apical Sling) in Advanced POP Repair.

Start date: September 9, 2022
Phase: N/A
Study type: Interventional

This is a prospective randomized controlled study, designed to assess the influence of posterior colporrhaphy and perineoplasty performed simultaneously with mesh-augmented sacrospinal fixation (apical sling) in advanced pelvic organ prolapse repair.

NCT ID: NCT05420831 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

Comparison of Vaginal and Laparoscopic Apical Fixation Techniques for Pelvic Organ Prolapse Treatment

Start date: September 9, 2022
Phase: N/A
Study type: Interventional

This is a prospective randomized controlled study, designed to compare efficacy and safety of two methods of apical fixation in patients with pelvic organ prolapse (POP) - sacrospinous hysteropexy (SSHP) with synthetic mesh and laparoscopic sacrohysteropexy (LSHP), and the impact of the surgery on quality of life.

NCT ID: NCT05312047 Active, not recruiting - Clinical trials for Urinary Incontinence

Continence After Vaginal Prolapse Surgery

Start date: April 4, 2022
Phase:
Study type: Observational

Urinary incontinence after surgical correction of pelvic organ prolapse (POP) could occur. This is a condition that decreases both patients' satisfaction and quality of life. Reports on the prevalence of urinary incontinence after POP surgery are controversial. Concomitant surgery for incontinence could reduce this prevalence, whereas it increases treatment costs and the likelihood of surgical complications. Therefore, it is of paramount importance to know the exact prevalence of urinary incontinence after POP surgery in our population and the potential risk factors associated with this condition.

NCT ID: NCT05192954 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

Comparing Postoperative Pain After Vessel Sealing Device Versus Conventional Suturing Methods for Vaginal Hysterectomy and Pelvic Reconstructive Surgery

Start date: January 28, 2022
Phase: N/A
Study type: Interventional

This study will investigate pain outcomes for patients undergoing vaginal hysterectomy with pelvic reconstructive surgery using the LigasureTM vessel sealing device as compared to conventional clamping and suturing methods.

NCT ID: NCT04480671 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

Impact of Level III Support Procedure on Enlarged Genital Hiatus After Minimally Invasive Sacrocolpopexy

MERIT
Start date: August 26, 2020
Phase: N/A
Study type: Interventional

This is a randomized controlled surgical trial evaluating the use of a concomitant posterior colporrhaphy and/or perineorrhaphy at the conclusion of minimally invasive sacrocolpopexy to narrow enlarged genital hiatuses in a population of women with pelvic organ prolapse. The study's primary outcome is the proportion of women at 6 months postoperatively who still have an enlarged genital hiatus. An exploratory sub-aim (as of October 2021) of the study is to evaluate the levator hiatal area as compared with the genital hiatus by using preoperative and postoperative transperineal ultrasounds. Subjects will be invited to participate, but is not required for study participation.

NCT ID: NCT04474275 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

The Effect of the Mode of Delivery to the Pelvic Floor Function

Start date: June 1, 2020
Phase:
Study type: Observational

The childbirth is one of the risk factors for pelvic organ prolapse. In order to prevent the pelvic organ prolapse, the physicians do not routinely advice any exercises after deliveries. The investigators wondered if the mode of deliveries such as ceserean section, vaginal route delivery with episiotomy or vaginal route delivery without episiotomy effect the pelvic floor function differently or not. In order to evaluate this, the investigators are planning to measure the muscle tonus in primiparous women.