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Pediatric Multiple Sclerosis clinical trials

View clinical trials related to Pediatric Multiple Sclerosis.

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NCT ID: NCT04660227 Completed - Clinical trials for Pediatric Multiple Sclerosis

Exercise Training in Pediatric-Onset Multiple Sclerosis Patients

Start date: November 23, 2020
Phase: N/A
Study type: Interventional

Multiple sclerosis is one of the leading causes of disability in young adults. It is known that patients with pediatric onset multiple sclerosis (POMS) experience their first demyelinating attack before the age of 18. However, studies conducted with individuals with pediatric onset of multiple sclerosis have been reported to be few and have affected parameters such as physical activity, fatigue balance and quality of life. Therefore, this study is planned to consist of two stages. These are the following stages; 1. Assessment of people with pediatric onset multiple sclerosis with the evaluation methods detailed below. After these evaluations, the relationship between the 6-minute walk test performance of the patients and other evaluations will be examined. Within the scope of the project, a publication will be prepared and uploaded with the data obtained from this stage. 2. The patients are divided into two groups, one group is included in the online exercise program, and the other group is included in the exercise program after being put on the waiting list.

NCT ID: NCT04441229 Completed - Clinical trials for Pediatric Multiple Sclerosis

Mobile Attentional Bias Modification Training in Pediatric MS

Start date: June 12, 2020
Phase: N/A
Study type: Interventional

This study will examine the feasibility of using a mobile ABMT application as a treatment modality in the Pediatric Multiple Sclerosis population. Participants will be asked to undergo one hour-long baseline evaluation, followed by at-home ABMT application sessions. Subjects will complete online REDCap or MyCap surveys weekly and at the end of the study.

NCT ID: NCT03137602 Completed - Clinical trials for Pediatric Multiple Sclerosis

ATOMIC (Active Teens With MultIple sClerosis) Teens: A Feasibility Study

Start date: March 7, 2018
Phase: N/A
Study type: Interventional

Taking part in recommended levels of physical activity in youth with MS may have an important and positive impact on disease symptoms, long-term disability and health outcomes. Unfortunately, youth with MS are highly inactive. In order to address this issue, the investigators have developed an MS-specific mobile application for teens called Active Teens with Multiple Sclerosis (ATOMIC). In this research the investigators will evaluate the feasibility of using the ATOMIC program in youth with MS. The results of this pilot study will provide the data necessary to ensure the ATOMIC program aligns with the needs of youth with MS.

NCT ID: NCT03067025 Completed - Clinical trials for Pediatric Multiple Sclerosis

Sleep, Physical Activity and Multiple Sclerosis Symptoms in Pediatric Multiple Sclerosis

Start date: March 7, 2018
Phase:
Study type: Observational

Most youth with MS experience symptoms such as depression and fatigue. In addition, cognitive issues, especially with attention and memory occur frequently. However, little is known about interventions that might work to improve these symptoms. In other work, the investigators have shown that higher levels of physical activity are associated with lower levels of depression and fatigue. Importantly, sleep problems are frequently encountered in youth with MS, and were seen in 60% of surveyed youth with MS in the investigators preliminary work. Modifiable lifestyle factors such as sleep and physical activity (PA) may play a key role in ameliorating common symptoms in pediatric MS. However, sleep has not been objectively described in pediatric MS, and the relationship between PA and sleep is poorly understood. This study aims to address these gaps.

NCT ID: NCT03066752 Completed - Clinical trials for Pediatric Multiple Sclerosis

Cognitive Dysfunction in MS: Using Altered Brain Oscillation to Link Molecular Mechanisms With Clinical Outcomes

Start date: March 27, 2017
Phase:
Study type: Observational

Up to 65% of patients with multiple sclerosis (MS) experience cognitive dysfunction. Diminution of mental capacity has a pervasive and profound impact on their quality of life. Subtle changes in white matter predict cognitive changes in these patients but how this disrupts brain function remains unclear. Development of effective therapeutics to restore normal cognition hinges on elucidating these functional changes. The investigators seek to uncover the patho-physiological basis for cognitive decline in MS. The investigators hypothesize that cognitive decline originates from disrupted gamma oscillations and that gamma oscillations are disrupted by molecular changes triggered by demyelination.

NCT ID: NCT01396343 Completed - Clinical trials for Pediatric Multiple Sclerosis

Environmental and Genetic Risk Factors for Pediatric Multiple Sclerosis

Start date: October 2011
Phase:
Study type: Observational

The purpose of this study is to better understand multiple sclerosis (MS) in children and adolescents, to learn if it differs from adult MS and to investigate if genes or environmental exposures or a combination of both put children and adolescents at risk for getting MS.