Beat Childhood Cancer Specimen Banking and Data Registry

Pediatric Cancer Clinical Trial

Official title: Specimen Banking With Clinical and Genomic Data Registry With the Establishment of Tumor Models for Pediatric Cancers

Status Recruiting

Clinical Trial Summary

This is an observational data registry study of all pediatric cancer patients at Atrium Health (AH) and participating Beat Childhood Cancer Consortium sites involving specimen banking and data collection.

Clinical Trial Description

This observational registry and banking study is being performed on a large cohort of patients who have been identified to receive molecular testing to better understand the relationship between genomic and molecular information and clinical outcomes, enabling timely and informed treatment decisions by physicians for cancer patients. We hypothesize that large gene panels, sequencing (DNA/RNA), and epigenetics of tumors can identify molecular aberrations in tumors that can be leveraged to offer more effective treatment. Findings may suggest additional research will be required to better understand the molecular underpinnings of the relationship between molecular abnormalities and disease. Banked specimens and the creation of tumor cell lines and xenograft models will enable this research to be performed. ;

Related Conditions & MeSH terms

• Pediatric Cancer

• NCT number: NCT04715178
• Study type: Observational [Patient Registry]
• Source: Milton S. Hershey Medical Center
• Contact: Abigail Moore
• Phone: 7175310003
• Email: amoore13@pennstatehealth.psu.edu
• Status: Recruiting
• Start date: February 2, 2021
• Completion date: January 2032