Pulmonary Mechanics During Minimally Invasive Repair of Pectus Excavatum

Status Recruiting

Clinical Trial Summary

The aim of the current study was to compare the effects of sevoflurane and desflurane on respiratory mechanics in patients undergoing repair of pectus excavatum.

Clinical Trial Description

The minimally invasive technique for pectus excavatum repair was introduced by Nuss and colleagues using a metal bar to lift the depressed chest wall. This surgical procedure is usually done under general anesthesia with tracheal intubation. After inserting metal bar into the chest wall, decreased lung compliance was shown. Previous studies demonstrated that administering desflurane during anesthesia resulted in marked increases in respiratory mechanical parameters, especially in the children with airway susceptibility. Our primary hypothesis was that desflurane would cause an increase in respiratory resistance and a decrease in lung compliance compared to sevoflurane during repair of pectus excavatum. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Supportive Care

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01486953
Study type	Interventional
Source	The Catholic University of Korea
Contact	Jeong Eun Kim, M.D, Ph.D
Phone	82-2-2258-6163
Email	moroo0201@catholic.ac.kr
Status	Recruiting
Phase	Phase 4
Start date	November 2011
Completion date	April 2014

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See also
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