PCD Clinical Trial
Official title:
A Clinical Investigation Determining the Discriminative Ability of the NIOX VERO NASAL to Differentiate Subjects With Primary Ciliary Dyskinesia From Healthy Controls
This is a multi-centre, single visit clinical investigation involving patients with known PCD
vs. age matched healthy volunteers. This study involves 1 visit which will last one (1) to
two (2) hours. Participants (and parent as applicable) will be asked for their consent to
participate in the study. A brief medical history will be recorded, including information
such as age, gender, height, weight, race, current medications and living environment. If the
participant is a PCD patient, they will also be asked about their disease history. Prior to
performing the nasal measurements, participants will receive instructions from study
personnel and have the opportunity to practice. All participants will have a brief nasal exam
and will also have to blow their nose before starting the measurements. Participants will be
asked to perform nasal nitric oxide measurements using the tidal breathing method followed by
the velum closed with expiration against resistance method.
The primary objective is to determine the feasibility and capability of the NIOX VERO to
discriminate participants with PCD from those that are healthy. Information collected in this
study will help researchers understand more about the diagnosis of and identification of
patients with PCD.
n/a