Clinical Trials Logo

Patent Ductus Arteriosus clinical trials

View clinical trials related to Patent Ductus Arteriosus.

Filter by:
  • Not yet recruiting  
  • Page 1

NCT ID: NCT06256211 Not yet recruiting - Clinical trials for Patent Ductus Arteriosus

Assessment of Therapeutic Effect of Rectal Vs. Intravenous Paracetamol in The Treatment of Patent Ductus Arteriosus (PDA) in Neonates

Start date: March 1, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

To compare the effectiveness of rectal vs. intravenous paracetamol in the medical treatment of significant PDA in neonates.

NCT ID: NCT06152796 Not yet recruiting - Clinical trials for Patent Ductus Arteriosus

Comparision Between Paracetamol and Ibuprofen in Closure of Patent Ductus Arteriosus

Start date: December 1, 2023
Phase: Phase 2
Study type: Interventional

To compare efficacy and safety of paracetamol and ibuprofen for the pharmacological closure of patent ductus arteriosus (PDA) in preterm infants.

NCT ID: NCT06045130 Not yet recruiting - Sepsis Clinical Trials

PUFAs in Preterm Infants

PIPI
Start date: September 21, 2023
Phase:
Study type: Observational

The research endeavors to examine the critical composition of Polyunsaturated Fatty Acids (PUFAs) in premature infants across different gestational stages and under varying disease conditions, and delineate the metabolic attributes of PUFAs in premature infants and their interplay with the onset of diseases. This study anticipates furnishing a theoretical foundation for the rationalization of PUFAs supplementation in premature infants and for informing strategies related to disease prevention and management.

NCT ID: NCT04964531 Not yet recruiting - Clinical trials for Patent Ductus Arteriosus

Effect of PDA Closure on the Left Ventricular Remodeling

Start date: July 2021
Phase:
Study type: Observational

failure of closure of the ductus arteriosus after birth results in a congenital anomaly known as patent ductus arteriosus. The large ductus can induce left side heart remodeling changes which could interfere with the normal cardiac function.

NCT ID: NCT04672629 Not yet recruiting - Clinical trials for Patent Ductus Arteriosus

Clinical Profile of Neonates Having Patent Ductus Arteriosus

Start date: April 1, 2021
Phase:
Study type: Observational

The study aims to evaluate the clinical presentation and course of PDA diagnosed at neonatal period in the neonatology unit of Assiut University Hospital for Children.

NCT ID: NCT04415554 Not yet recruiting - Clinical trials for Patent Ductus Arteriosus

Aminoglycosides and Duct

Start date: July 2021
Phase:
Study type: Observational

The aim of the study is to assess the effect of aminoglycoside treatment on ductal closure in preterms

NCT ID: NCT02910609 Not yet recruiting - Clinical trials for Patent Ductus Arteriosus

International Experience in Timing And Choices for Ductal Closure in Patent Ductus Arteriosus:INTERPDA Trial

Start date: January 2017
Phase: N/A
Study type: Observational [Patient Registry]

The three options for the treatment of patent ductus arterioles (PDA) in preterm infants are conservative approach, pharmacological intervention and surgical ligation. There is not any randomized-controlled trial that demonstrates the superiority of these approaches in preterm infants.

NCT ID: NCT02894970 Not yet recruiting - Clinical trials for Pulmonary Hypertension

A New Device for Measuring of Lung Photoplethysmography and Pulmonic Arterial Saturation

Start date: October 2016
Phase: N/A
Study type: Observational

To evaluate feasibility of photoplethysmography (PPG) of pulmonary arteries in adults children and neonates and to compare normal controls to premature newborns suffering from patent ductus arteriosus and neonates suffering from pulmonary hypertension.

NCT ID: NCT00616382 Not yet recruiting - Clinical trials for Patent Ductus Arteriosus

Treating the Resistant Patent Ductus Arteriosus (PDA)

Start date: March 2008
Phase: Phase 2
Study type: Interventional

Persistent postnatal ductal patency may have significant adverse hemodynamic effects, frequently necessitating therapeutic intervention in order to facilitate ductal closure. Medical therapy for patency of the ductus arteriosus is successful mediating ductal closure in approximately 70% of treated infants. In a recent study in our population, 17% of the babies showed no ductal response to the first course of treatment and 9.4% of our study infants eventually underwent surgical ligation of the ductus after failure of medical therapeutic closure.We propose to evaluate and compare two alternate therapeutic approaches to ductal closure in babies who do not respond to initial therapy.