Relationship Between Constitutional Varus Knee and Patellofemoral Pain

Patellofemoral Pain Syndrome Clinical Trial

Official title:

Research on the Relationship Between Constitutional Varus Knee and Patellofemoral Pain

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT03450824
• Other study ID #: 113YY-LUNLI-2018002
• Status: Terminated
• Start date: March 23, 2018
• Est. completion date: June 15, 2023

Study information

• Verified date: June 2023
• Source: 113th Hospital of Chinese People's Liberation Army
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study aims to research on the relationship between constitutional varus knee and patellofemoral pain. The standardized standing whole-lower-extremity radiographs, the knee lateral view and skyline view of the participants will be taken. The hip-knee-ankle angle will be obtained from the radiographs. According to the hip-knee-ankle angle, the knees will be labelled knee varus or knee nonvarus. The knee varus incidences of the two groups will be determined and compared.

Description:

The patellofemoral joint will be assessed in the skyline view and lateral view. The hip-knee-ankle angle will be obtained from the standing whole-lower-extremity radiographs. According to the hip-knee-ankle angle, the knees will be labelled knee varus or knee nonvarus. The knee varus incidences of the two groups will be determined and compared. It is hypothesized that constitutional varus knee is a risk factor for patellofemoral pain.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 21
• Est. completion date: June 15, 2023
• Est. primary completion date: June 15, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 35 Years

Eligibility

Inclusion Criteria:

• Patellofemoral pain during physical activities such as running, jumping, squatting, and going up or down stairs for at least 4 weeks.

• The onset of pain is required to be atraumatic in nature.

• Exhibit two of the following clinical criteria on assessment: pain on direct compression of the patella against the femoral condyles with the knee in full extension, tenderness of the posterior surface of the patell on palpation, pain on resisted knee extension, and pain with isometric quadriceps muscle contraction against suprapatellar resistance with the knee in 15° of flexion.

• Negative findings in the examination of knee ligaments, menisci, bursae, synovial plicae, Hoffa's fat pad, iliotibial band, and the hamstring, quadriceps, and patellar tendons and their insertions.

Exclusion Criteria:

• With patellofemoral instability, or With other knee diagnoses.

• Any previous surgery or severe trauma in the affected limb.

• Inflammatory joint disease or tumors in the affected limb.

Related Conditions & MeSH terms

• Patellofemoral Pain Syndrome

Intervention

Other:
• No intervention
The standardized standing whole-lower-extremity radiographs, the knee lateral view and skyline view of the participants will be taken.

Locations

Country	Name	City	State
China	Orthopaedics clinic, No.113 Hospital of Chinese People's Liberation Army	Ningbo	Zhejiang

Sponsors (2)

Lead Sponsor	Collaborator
113th Hospital of Chinese People's Liberation Army	Air Force Military Medical University, China

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The hip-knee-ankle angle	The HKA angle was determined by measuring the angle between the mechanical axis of the femur and the mechanical axis of the tibia.	1 day
Secondary	Patellar alignment	The lateral displacement of the patella was defined as the proportion of the distance from the lateral edge of the patella to a line drawn perpendicular to a line passing along the most anterior margin of the medial and lateral trochlear facets, by the length of the maximum width of the patella. The tilting angle of the patella was defined as the angle formed by a line joining the maximum width of the patella and a line passing along the most anterior margin of the medial and lateral trochlear facets.	1 day
Secondary	The width of of the patellofemoral joint space	The width of the joint space at the mid-point of the medial and lateral patellofemoral joint is measured on the skyline view.	1 day
Secondary	Trochlear morphology	The sulcus angle was defined as the angle between the medial and lateral trochlear facets. The vertex of the angle was the deepest portion of the trochlea.	1 day
Secondary	Patellar height	The Insall-Salvati ratio is the ratio between the length of the patellar tendon and the superior-inferior length of the patella.	1 day