Effect of Hip & Core Muscle Strengthening for Patellofemoral

Status Completed

Clinical Trial Summary

The purpose of this research is to develop and test the feasibility of an exercise intervention for persons with painful knee osteoarthritis involving the patella (kneecap). Participants in the patellofemoral osteoarthritis (PFOA) group will be treated with a 6-week supervised exercise program that targets strengthening the hip and trunk core muscles. Painfree control participants will attend one session to gather biomechanical, strength, and function data for use in comparison to the patellofemoral osteoarthritis group. Feasibility outcomes include adherence to the treatment program, recruitment, and retention. It is hypothesized that PFOA group participants will change score on a knee pain and function questionnaire by the minimum clinically important difference score for positive improvement at the end of the 6-week intervention program.

Clinical Trial Description

The investigators propose to develop and test the feasibility of a 6-week supervised hip and core muscle exercise intervention for persons with painful patellofemoral osteoarthritis (PFOA), a common condition for middle-aged and older adults. Currently there is limited evidence regarding effective conservative interventions for PFOA, a chronic condition that is painful and limits function and quality of life. Exercise is recommended as a first-line treatment for knee osteoarthritis, but the optimal type of exercise for PFOA is unknown. This intervention is based upon similar programs shown to improve pain and function in younger persons with patellofemoral pain, a condition that may lead to PFOA. Feasibility outcomes include adherence to the treatment program, recruitment, retention, and the impact of the intervention on participants' pain and function at 6-weeks and 6 months after finishing the program. The investigators will also compare PFOA participants to a matched pain-free volunteer control group to explore the differences in their biomechanics, muscle strength, pain report, and function at baseline. Data from this feasibility study will be used to design a future randomized controlled trial investigating the efficacy of conservative exercise interventions for PFOA. The investigators' overarching goal is to develop a conservative exercise intervention that improves the symptoms, function, and quality of life of persons with PFOA. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02825238
Study type	Interventional
Source	University of the Sciences in Philadelphia
Contact
Status	Completed
Phase	N/A
Start date	October 23, 2012
Completion date	December 11, 2015

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT06060730` - Measurement Properties of the Turkish Version of the Patellofemoral Pain and Osteoarthritis Subscale of the KOOS
Recruiting	`NCT04937998` - PRP Versus HA IN OSTEOARTHRITIS OF THE PATELLOFEMORAL JOINT	N/A
Completed	`NCT03281837` - 2 Weekly Intra-articular Hyaluronan Knee Injections, Given 1 wk. Apart, of HYMOVIS Combined With Physical Exercise Program (PEP) Compared to PEP Alone, in Relatively Young, Active Population of Subjects With Patellofemoral Osteoarthritis (PFOA) and/or Tibiofemoral Osteoarthritis (TFOA)	N/A
Completed	`NCT05184439` - Evaluation of Adductor Magnus Tenodesis in Patients With Recurrent Patellar Dislocation.
Not yet recruiting	`NCT04332900` - Proximal and Distal Therapeutic Approach in Pain and Lower Limb Kinematic in People With Patellofemoral Osteoarthritis	N/A
Completed	`NCT02610192` - nSTRIDE APS in Females With Primary Patellofemoral Osteoarthritis	N/A
Recruiting	`NCT06163573` - Treatment of Patellofemoral Osteoarthritis With Engineered Cartilage.	Phase 2
Completed	`NCT04589871` - Taping Technique With Supervised Exercises Protocol on Pain and Functional Status in Individuals With Arthritis	N/A
Active, not recruiting	`NCT04817969` - Persona Ti-Nidium Post-Market Clinical Follow-up	N/A
Active, not recruiting	`NCT04772625` - Failure Analysis of Patellofemoral Arthroplasty
Terminated	`NCT00816647` - A Prospective Randomized Study of Medial Patellofemoral Ligament (MPFL) Reconstruction	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Effect of Hip and Core Muscle Strengthening for Patellofemoral Osteoarthritis: A Feasibility Study

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms