Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to evaluate clinical outcomes following a single injection of nSTRIDE Autologous Protein Solution in females with isolated patellofemoral osteoarthritis. A secondary objective of this study is to document the duration of treatment effect following nSTRIDE injection.


Clinical Trial Description

Clinical trials have, in general, formally demonstrated the effectiveness and safety of various autologous therapies for the treatment of knee OA. Differences in the processing of autologous therapies can yield substantial differences in the resulting output. Thus, making generalizations regarding the effectiveness across these autologous therapies is more complicated. Each autologous therapy requires independent efficacy evaluation. nSTRIDE APS has been shown to decrease pain, increase function and have a favorable safety profile in a pilot trial. Further, demonstration of the treatment effects in patellofemoral osteoarthritis, an important subset of knee osteoarthritis is lacking. This study will evaluate a population of female patients with patellofemoral osteoarthritis in which treatment with other modalities provides limited/short lived relief with the hope that APS treatment will provide and extend relief to these patients. The study will document the treatment effects and timeline of treatment effects for nSTRIDE APS following a single injection (per symptomatic knee). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02610192
Study type Interventional
Source Zimmer Biomet
Contact
Status Completed
Phase N/A
Start date March 2016
Completion date June 2018

See also
  Status Clinical Trial Phase
Completed NCT06060730 - Measurement Properties of the Turkish Version of the Patellofemoral Pain and Osteoarthritis Subscale of the KOOS
Recruiting NCT04937998 - PRP Versus HA IN OSTEOARTHRITIS OF THE PATELLOFEMORAL JOINT N/A
Completed NCT02825238 - Effect of Hip and Core Muscle Strengthening for Patellofemoral Osteoarthritis: A Feasibility Study N/A
Completed NCT03281837 - 2 Weekly Intra-articular Hyaluronan Knee Injections, Given 1 wk. Apart, of HYMOVIS Combined With Physical Exercise Program (PEP) Compared to PEP Alone, in Relatively Young, Active Population of Subjects With Patellofemoral Osteoarthritis (PFOA) and/or Tibiofemoral Osteoarthritis (TFOA) N/A
Completed NCT05184439 - Evaluation of Adductor Magnus Tenodesis in Patients With Recurrent Patellar Dislocation.
Not yet recruiting NCT04332900 - Proximal and Distal Therapeutic Approach in Pain and Lower Limb Kinematic in People With Patellofemoral Osteoarthritis N/A
Recruiting NCT06163573 - Treatment of Patellofemoral Osteoarthritis With Engineered Cartilage. Phase 2
Completed NCT04589871 - Taping Technique With Supervised Exercises Protocol on Pain and Functional Status in Individuals With Arthritis N/A
Active, not recruiting NCT04817969 - Persona Ti-Nidium Post-Market Clinical Follow-up N/A
Active, not recruiting NCT04772625 - Failure Analysis of Patellofemoral Arthroplasty
Terminated NCT00816647 - A Prospective Randomized Study of Medial Patellofemoral Ligament (MPFL) Reconstruction N/A