Partial Onset Seizures Clinical Trial
Official title:
A Multicentre, Randomized, Double-blind, Placebo Controlled, Parallel-group Study in Children With Inadequately Controlled Partial Onset Seizures to Investigate Efficacy, Safety and Tolerability of TRI476 (Oxcarbazepine) as Adjunctive Therapy
This study is designed to provide short term efficacy and safety data of TRI476 in children with inadequately-controlled partial seizures. Patients will be randomized into either drug treatment or placebo group at 1:1 ratio, and receive their respective treatment for 8 weeks. The purpose of study is to confirm that TRI476 as adjunctive therapy is effective and safe.
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01710657 -
A Trial to Evaluate the Efficacy and Safety of Adjunctive Therapy With Lacosamide in Adults With Partial-Onset Seizures
|
Phase 3 | |
| Completed |
NCT02072824 -
A Safety, Efficacy, and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric Subjects <4 Years of Age With Partial Onset Seizures.
|
Phase 3 | |
| Completed |
NCT01830868 -
A Post-marketing Observational Study Of The Use Of Zonisamide (ZNS) in the Adjunctive Treatment Of Adult Patients With Partial Onset Seizures (Study E2090-E044-410) (ZOOM)
|
||
| Completed |
NCT03201900 -
Study for Verification of Efficacy and Safety for Perampanel Monotherapy in Untreated Participants With Partial Onset Seizures (Including Secondarily Generalized Seizures (FREEDOM Study)
|
Phase 3 | |
| Completed |
NCT01338805 -
Phase II BGG492 Capsule Extension for Partial Epilepsy
|
Phase 2 | |
| Completed |
NCT01147003 -
Efficacy and Safety of BGG492 as Adjunctive Treatment in Patients With Partial Onset Seizures
|
Phase 2 | |
| Completed |
NCT01407523 -
An Open Label Study of L059 Intravenous (IV) in Japanese Epilepsy Subjects With Partial Onset Seizures
|
Phase 2 | |
| Completed |
NCT04252846 -
A Study to Investigate Dosage, Effectiveness, and Safety of Perampanel When Used as First Add-on Therapy in Participants >=12 Years With Partial Onset Seizures With or Without Secondary Generalization or With Primary Generalized Tonic-Clonic Seizures Associated With Idiopathic Generalized Epilepsy
|
||
| Completed |
NCT01051193 -
Long-term Safety and Tolerability of TRI476 (Oxcarbazepine) in Children With Inadequately Controlled Partial Onset Seizures
|
Phase 2/Phase 3 | |
| Completed |
NCT03836924 -
A Study to Assess Safety and Efficacy of Perampanel in Indian Participants as an Adjunctive Treatment in Partial Onset Seizures With or Without Secondary Generalized Seizures in Participants With Epilepsy Aged 12 Years or Older
|
||
| Completed |
NCT01506882 -
An Open Label Study of Levetiracetam Monotherapy in Patients With Newly Diagnosed Focal Epilepsy
|
Phase 3 | |
| Completed |
NCT03288129 -
Study to Evaluate the Efficacy and Safety of Perampanel as Monotherapy or First Adjunctive Therapy in Subjects With Partial Onset Seizures With or Without Secondarily Generalized Seizures or With Primary Generalized Tonic-Clonic Seizures
|
Phase 4 | |
| Withdrawn |
NCT01167335 -
Evaluate the Efficacy of BGG492 as Adjunctive Treatment in Patients With Refractory Partial Onset Seizures
|
Phase 2 | |
| Completed |
NCT01830400 -
A Post-marketing Study Evaluating Eslicarbazepine Acetate (ESL) as Adjunctive Treatment in Partial-Onset Seizures (Study E2093-E044-404) (EPOS)
|
N/A | |
| Completed |
NCT00655486 -
Study to Assess the Long-term Safety of Oral Lacosamide in Subjects With Partial-onset Seizures
|
Phase 3 | |
| Completed |
NCT00655551 -
Safety of Intravenous Lacosamide Dose Followed by Twice Daily Oral Lacosamide in Subjects With Partial-onset Seizures
|
Phase 3 | |
| No longer available |
NCT01871233 -
An Extended Access Program for Perampanel
|