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Paralysis clinical trials

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NCT ID: NCT04287673 Completed - Clinical trials for Cerebral Palsy, Spastic

Associated Disorders of Locomotion and Postural Control of Axial Segments in Cerebral Palsy

Start date: December 20, 2016
Phase: N/A
Study type: Interventional

Gait abnormalities, which occur in Cerebral Palsy (CP), are characterized usually by a toe-to-floor or a plantar-to-floor initial contact (equinus gait), followed by an early braking of the tibia's forward progression (during ankle dorsiflexion). This causes consequently a trunk deceleration. Moreover, children with CP have difficulties to stabilize the trunk and the head in the space, and that could have impact on gait. If equinus gait is often attributed to the triceps surae spasticity, recent works suggest rather that this early braking of the dorsiflexion could be a motor adaptation to axial postural control difficulties. This thesis project aims firstly to attest that locomotor disorders are related to these difficulties in the stabilization of the axial body segments in children with CP and, secondly, to show that improving the trunk and head postural control with a specific rehabilitation protocol could reduce the early braking of the dorsiflexion and, consequently, the gait abnormalities observed in CP.

NCT ID: NCT04263701 Completed - Cerebral Palsy Clinical Trials

Dual Task Training in Spastic Cerebral Palsy

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

This study aims to investigate the effects of dual task training on gait and balance parameters, gross motor function skills, functional mobility skills, functional independence levels and health-related quality of life o in children with spastic diplegic cerebral palsy. The clinical study's hypothesis is the dual task training programs are superior to conventional physiotherapy programs to improve the parameters in spastic diplegic cerebral palsy.

NCT ID: NCT04256187 Completed - Cerebral Palsy Clinical Trials

Pros and Cons of Botulinum Injection Treatment in Cerebral Palsy

Start date: November 1, 2019
Phase:
Study type: Observational

The aim of this study is to quantitatively record the opinions regarding the pros and cons of this treatment of the caregivers of children with cerebral palsy who had botulinum toxin applied in investigators' clinic.

NCT ID: NCT04243590 Completed - Cerebral Palsy Clinical Trials

Turkish Version of Hand-Use-at-Home Questionnaire

Start date: February 1, 2020
Phase:
Study type: Observational

To investigate the validity and reliability of the Turkish Version of parent-rated Hand-Use-at- Home questionnaire (HUH) in children with neonatal brachial plexus palsy or unilateral cerebral palsy.

NCT ID: NCT04231227 Completed - Cerebral Palsy Clinical Trials

The Validity and Reliability of the Turkish Version of TASC and the Relationship Between SMC and Motor Functions

Start date: July 1, 2018
Phase:
Study type: Observational

Selective motor control (SMC) impairment in children with cerebral palsy (CP) includes movement patterns dominated by flexor or extensor synergy affecting functional movements. The research was designed to investigate the validity and the reliability of the Turkish version of the Test of Arm Selective Control (TASC) (which is improved to evaluate SMC in children with spastic CP) and in order to provide more understanding of the relationship between SMC and upper extremity and gross motor functions. The study included 21 hemiplegic, 11 diplegic and 4 quadriplegic children with CP whose ages are 4 to 18 years and Gross Motor Function Classification System (GMFCS) level changes from 1 to 4, and their parents. In order to evaluate the gross motor function of children, GMFCS and the ability to hold objects with their hands in daily activities were evaluated with Manual Ability Classification System (MACS). ABILHAND-Kids scale was applied to evaluate upper extremity performance. TASC scale was used to evaluate the upper extremity SMC of children.

NCT ID: NCT04222049 Completed - Cerebral Palsy Clinical Trials

Application of Vibration Wave Therapy to the Children Suffering From Cerebral Palsy and Tongue Spastic Dysarthria

Start date: July 15, 2019
Phase: N/A
Study type: Interventional

Vibration therapy is the widely used in many neurological disorders for different type of problems. Recently, it is being used by researchers for the betterment of motor disorders and muscle movements of the cerebral palsy patients and significant results are obtained. Investigators are conducting this research to explore that whether this therapy can have some effect on the Spastic Tongue Dysarthria of the Cerebral Palsy patients.

NCT ID: NCT04193072 Completed - Image, Body Clinical Trials

Imagery Ability in Obstetric Brachial Plexus Palsy

Start date: October 2, 2017
Phase:
Study type: Observational

Obstetric brachial plexus palsy (OBPP) is the paralysis of the ipsilateral upper extremity after a brachial plexus injury that occurs during labor. Imagery is to rehearse sensorial experiences in the mind such as auditory, visual, tactile, olfactory, gustatory or kinesthetic sensation. Imagery is used as a new technique in rehabilitation recently. Various studies have reported the importance of imagery and using imagery as a rehabilitation technique in different neurologic and orthopedic conditions. This study aimed to evaluate imagery ability in children with OBPP.

NCT ID: NCT04185415 Completed - Clinical trials for Progressive Supranuclear Palsy

A Study to Test the Safety and Tolerability of UCB0107 in Study Participants With Progressive Supranuclear Palsy (PSP)

Start date: December 3, 2019
Phase: Phase 1
Study type: Interventional

The purpose of the study is to assess the safety and tolerability of UCB0107 in study participants with Progressive Supranuclear Palsy (PSP).

NCT ID: NCT04179682 Completed - Rehabilitation Clinical Trials

A Pilot Study of Constraint Induced Movement Therapy in Preschool Cerebral Palsy After Botulism Toxin Injection

Start date: July 1, 2014
Phase: N/A
Study type: Interventional

To establish a pilot randomized, crossover study on applying 2 constraint-induced movement therapy (CIMT) interventions in children with hemiplegic cerebral palsy after botulinum toxin injection during preschool education.

NCT ID: NCT04173364 Completed - Clinical trials for Diaphragmatic Paralysis

Interscalene Block and Dysfunction Diaphragmatic

NUMEROBIS
Start date: October 29, 2019
Phase: Phase 3
Study type: Interventional

The study seeks to show that interscalene injection of a small volume (<8ml) of ropivacaine at a low concentration (0.1%) reduces the frequency of hemi-diaphragmatic paresis compared to low volume injection at the standard concentration (0.5%) in patients undergoing arthroscopic shoulder surgery with ISB.