Papilla, Dentinal; Calcification Clinical Trial
Official title:
Efficiency of Concentrated Growth Factor in the Surgical Treatment of Multiple Adjacent Papillary Losses: a Controlled, Examiner-blinded Clinical Study
The aim of this study was to evaluate the efficacy of concentrated growth factor (CGF) in applied in the regenerative treatment of multiple adjacent papillary black triangles (MAPBT) occured as a result of soft tissue loss. Interdental papillary regeneration was evaluated with the change in the area of interproximal spaces calculated on each of the intraorally scanned images obtained with digital impressions of the interproximal space with irregular borders.This controlled, examiner-blinded, clinical study included of 40 patients with 120 open embrasures which resulted from papillary loss in adjacent teeth in the anterior maxillary esthetic zone resulting in black triangles (BTs). Then patients were randomly assigned to receive surgical regenerative periodontal treatment(test) or periodontal care(control)The test group was formed of 20 patients with 60 adjacent papillary defects . A control group was formed of 20 patients with 60 adjacent papillary defects.. A total of 480 images obtained with the digital impressions . Evaluations of the test group were made preoperatively and at 3, 6 and 12 months postoperatively. For the control group, oral hygiene instruction was provided. Control group is evaluated by the same procedure with test group but the surgical part is not performed. Lost interdental papillary area (PA)were calculated. In the test group, the percentage of papillary filling, the presence of keratinized gingiva, the thickness of papillary gingiva, blood thrombocyte count and mean platelet volume values(MPV) were recorded.
The treatment of open gingival embrasures, which are also known as black triangles (BT) or
black holes, and cause esthetic, functional and phonetic problems in the anterior region, has
become an area of interest in current periodontal treatment.Surgical, non-surgical and
prosthetic methods are applied in the treatment of BT, which can be seen in more than half of
adults. This study aimed to evaluate the efficacy of concentrated growth factor (CGF) in
regenerating interdental papillary of multiple adjacent papillary black triangles (MAPBT)
occured as a result of soft tissue loss. Interdental papillary regeneration was evaluated
with the change in the area of interproximal spaces calculated on each of the intraorally
scanned images obtained with digital impressions of the interproximal space with irregular
borders.
This controlled, examiner-blinded, randomized clinical study included 160 teeth of 40
patients with 120 open embrasures which resulted from papillary loss in adjacent teeth in the
anterior maxillary esthetic zone resulting in black triangles (BTs). The test group was
formed of 20 patients with 60 adjacent papillary defects undergoing minimally invasive
surgery for papillary regeneration with CGF. A control group was formed of 20 patients with
60 adjacent papillary defects who were not included surgical treatment. A total of 480 images
obtained with the digital impressions method of each interdental papillary region in each
patient were uploaded to a special software. Evaluations of the test group were made
preoperatively and at 3, 6 and 12 months postoperatively. For the control group, oral hygiene
instruction was provided. Control group is evaluated by the same procedure with test group
but the surgical part is not performed. Lost interdental papillary area (PA)were calculated
between the two central teeth, between the lateral and central teeth, and between the lateral
and canine teeth prior to the treatment and at pro-treatment periods of 3, 6 and 12 months in
both of the groups. In the test group, the percentage of papillary filling, the presence of
keratinized gingiva, the thickness of papillary gingiva, blood thrombocyte count and MPV
values were recorded.
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