Psychodynamic Therapy for Treating Panic Disorder

Panic Disorder Clinical Trial

Official title:

Randomized Controlled Trial of Psychodynamic Psychotherapy vs. Applied Relaxation for Panic Disorder

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00128388
• Other study ID #: K23MH001849
• Secondary ID: K23MH001849DSIR
• Status: Completed
• Phase: Phase 2/Phase 3
• First received: August 5, 2005
• Last updated: June 26, 2013
• Start date: February 2000
• Est. completion date: July 2005

Study information

• Verified date: June 2013
• Source: Weill Medical College of Cornell University
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Interventional

Clinical Trial Summary

This study will determine the effectiveness of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training in treating adults with panic disorder.

Description:

This is a randomized controlled trial of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training, a less active form of treatment in other studies, for adults with primary Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) panic disorder.

Forty nine patients who have signed written consent who have primary DSM-IV panic disorder have been entered into the study. Randomization has been stratified by presence of major depression and use of psychoactive, anti-panic medications. Medications, if present, have been held constant. All patients have received 24 sessions of either psychodynamic psychotherapy, or applied relaxation training for panic disorder. This study is currently closed for recruitment, although final follow-up assessments have yet to be completed.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 49
• Est. completion date: July 2005
• Est. primary completion date: January 2005
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 55 Years

Eligibility

Inclusion Criteria:

• 18-55 years old

• Primary DSM-IV panic disorder with or without agoraphobia

• Severity 5/8 minimum on the Anxiety Disorders Interview Schedule

Exclusion Criteria:

• Psychosis

• Unstable medication dosage

• Unwilling to discontinue ongoing psychotherapy

• Organic mental syndrome

• Substance use or abuse

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Panic Disorder

Intervention

Other:
• PFPP
Psychoanalytic Psychotherapy for panic disorder
• ART
Applied Relaxation Training

Locations

Country	Name	City	State
United States	Weill Medical College	New York City	New York

Sponsors (2)

Lead Sponsor	Collaborator
Weill Medical College of Cornell University	National Institute of Mental Health (NIMH)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	PDSS (panic disorder severity scale)		termination, 2, 4, 6, 12 month f/u	No
Secondary	SDS (Sheehan disability scale)		termination, 2, 4, 6, 12 month f/u	No
Secondary	HARS (Hamilton anxiety rating scale)		termination, 2, 4, 6, 12 month f/u	No
Secondary	HDRS (Hamilton depression rating scale)		termination, 2, 4, 6, 12 month f/u	No