Validation of the Panic Screening Score in Patient With Unexplained Chest Pain

Panic Attack Clinical Trial

Official title:

A Prospective Cohort Study to Refine and Validate the Panic Screening Score for Identifying Panic Attacks Associated With Unexplained Chest Pain in the Emergency Department

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02405052
• Other study ID #: 286934
• Status: Recruiting
• Phase: N/A
• First received: March 29, 2015
• Last updated: March 31, 2015
• Start date: July 2013

Study information

• Verified date: March 2015
• Source: Hôtel-Dieu de Lévis
• Contact: Guillaume Foldes-Busque, Ph.D
• Phone: 418-835-7121
• Email: guillaume.Foldes-Busque[@]psy.ulaval.ca
• Is FDA regulated: No
• Health authority: Canada: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

Panic-like anxiety ( panic attacks with or without panic disorder), a highly treatable condition, is the most prevalent condition associated with unexplained chest pain in the emergency department. Panic-like anxiety may be responsible for a significant portion of the negative consequences of unexplained chest pain, such as functional limitations and chronicity. However, more than 92% of panic-like anxiety cases remain undiagnosed at the time of discharge from the emergency department. The 4-item Panic Screening Score questionnaire was derived in order to increase the identification of panic-like anxiety in emergency department patients with unexplained chest pain.

The goals of this prospective cohort study are to (1) refine the Panic Screening Score; (2) validate the revised version of the Panic Screening Score; (3) measure the reliability of the revised version of the Panic Screening Score and (4) assess the acceptability of the instrument among emergency physicians.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 3000
• Est. primary completion date: December 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

Presenting unexplained chest pain as defined by:

• the absence of an identifiable cause (e.g., pneumothorax,pneumonia),

• the absence of chest trauma,

• the absence of new malignant cardiac arrhythmia, and

• a score of 2 or less on the modified version of the thrombolysis in myocardial infarction score.

Exclusion Criteria:

• presence of a terminal illness;

• presence of a severe communication problem that could interfere with the administration of the questionnaire;

• presence of a psychotic state, a major cognitive deficit or other condition that could invalidate the interview;

• being legally incompetent.

Study Design

Observational Model: Cohort, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Chest Pain
• Noncardiac Chest Pain
• Panic Attack

Intervention

Other:
• No intervention
Validation of the Panic Screening Score

Locations

Country	Name	City	State
Canada	Centre de recherche, CSSS Alphonse-Desjardins, Centre hospitalier affilié universitaire de Lévis	Lévis	Quebec

Sponsors (1)

Lead Sponsor	Collaborator
Hôtel-Dieu de Lévis

Country where clinical trial is conducted

Canada, 

References & Publications (1)

Foldes-Busque G, Denis I, Poitras J, Fleet RP, Archambault P, Dionne CE. A prospective cohort study to refine and validate the Panic Screening Score for identifying panic attacks associated with unexplained chest pain in the emergency department. BMJ Open. 2013 Oct 25;3(10):e003877. doi: 10.1136/bmjopen-2013-003877. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Accuracy of the Panic Screening Score		3 years	No