Pancreatic Adenocarcinoma Gene Environment Risk Study

Pancreatic Cancer Clinical Trial

— PAGER  

Official title:

The Pancreatic Adenocarcinoma Gene Environment Risk Study -A Prospective Cohort Study of Patients at Risk or Having Pancreatic Disease

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT00912717
• Other study ID #: STUDY19070256
• Status: Recruiting
• Start date: January 2004
• Est. completion date: December 2027

Study information

• Verified date: October 2023
• Source: University of Pittsburgh
• Contact: Randall E Brand, MD
• Phone: 412-623-3105
• Email: brandre[@]upmc.edu
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

After informed consent, participants will be asked to complete a medical/family history questionnaire and provide a blood sample. Some participants may also be asked to provide a urine sample. Individuals undergoing procedures that require collection of biological samples for clinical purposes may have these samples saved for research purposes. Participants will also be asked for their permission for study investigators to access medical records and/or recontact them for updates to their medical and family histories. Data and biospecimens will be stored for potential future research projects.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 10000
• Est. completion date: December 2027
• Est. primary completion date: December 2027
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Histologically confirmed or CT confirmed diagnosis of pancreatic adenocarcinoma

• Subjects with abnormal imaging study (CT, MRI, MRCP, EUS)

• Control subjects with a clinical diagnosis of a pancreas, liver, or intestinal condition

• Control subject with acute pancreatitis

• Control subject with chronic pancreatitis

• Control subject with biliary obstruction

• Control subject with pancreatic cyst

• Member of a high risk family (= 1 close relative with pancreatic cancer)

• Healthy control (without any of the above conditions)

Exclusion Criteria:

• Under the age of 18 years

• Unable to give informed consent

• Inability to travel to Pittsburgh for in-person enrollment

Related Conditions & MeSH terms

• Adenocarcinoma
• Pancreatic Cancer

Locations

Country	Name	City	State
United States	University of Pittsburgh	Pittsburgh	Pennsylvania

Sponsors (1)

Lead Sponsor	Collaborator
University of Pittsburgh

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The data will be used in cohort association studies. Endpoints will depend on the number of patients in the study and the number of markers that are being evaluated.		10 years