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Clinical Trial Summary

This is an open-label, multicenter, Phase 1/2 study evaluating the safety and efficacy of CTX131™ in subjects with relapsed or refractory solid tumors.


Clinical Trial Description

An open-label, multi-center Phase 1/2 study of CTX131 in subjects with relapsed/refractory solid tumors. CTX131 is an is allogeneic CD70- directed chimeric antigen receptor (CAR) T cell immunotherapy comprised of allogeneic T cells that are genetically modified ex vivo using CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats/ CRISPR associated protein 9) gene editing components (single guide RNA and Cas9 nuclease). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05795595
Study type Interventional
Source CRISPR Therapeutics
Contact Central Trials
Phone +1 (877) 214-4634
Email MedicalAffairs@crisprtx.com
Status Recruiting
Phase Phase 1/Phase 2
Start date March 13, 2023
Completion date May 2030

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