Clinical Trials Logo
  1. Home
  2. Pain, Procedural
  3. NCT06331663

SPI and Remifentanil in Skull Pin Fixation

Pain, Procedural Clinical Trial

Official title:
To Explore the Optimal Dose of Remifentanil for Skull Pin Fixation Under Surgical Pleth Index Monitor in Intracranial Surgery

Clinical Trial Summary

Forty patients were enrolled, and all patients used total intravenous anesthesia (remifentanil-propofol based total intravenous analgesia) as anesthesia induction and maintenance. According to the preliminary data of this department, patients who underwent intracranial surgery for skull pin fixation used remifentanil 5.0-6.0 ng/ml, while the hemodynamics is relatively stable. Therefore, when this plan is implemented, the patient needs to be under the same depth of anesthesia (monitored by electroencephalography, maintaining a value of 40-60), first start with remifentanil 5.0 ng/ml, and use the up and down method as adjust 0.5 ng/ml of concentration of remifentanil each time. Inadequate antinociception (Surgical Pleth Index(SPI) > 80 and hyperdynamics (the increased heart rate (HR) and mean blood pressure (MBP) above 20% of baseline or HR>100bpm and arterial blood pressure(ABP)>180/100mmHg)) is defined as failure, therefore we increase remifentanil by 0.5 ng/ml; otherwise, the setting is considered successful without abovementioned situations. Data collection: heart rate, mean blood pressure, Surgical Pleth Index, bispectral Index, pulse pressure variance, systolic pressure variance, concentrations of propofol and remifentanil before 2 mins, during, 5, and 15 mins of skull pin fixation were recorded and analyzed.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06331663
Study type Interventional
Source Kaohsiung Medical University Chung-Ho Memorial Hospital
Contact
Status Not yet recruiting
Phase Phase 4
Start date April 1, 2024
Completion date June 20, 2024
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05458037 - RCT of Pain Perception With Fast and Slow Tenaculum Application N/A
Recruiting NCT05378581 - Use of Virtual Reality Mask During Blood and Skin Allergic Tests in 7 to 13 Children N/A
Not yet recruiting NCT05418114 - Lignocaine Only Versus Lignocaine Plus Magnesium Sulphate for Pain Relief After Episiotomy. Phase 4
Completed NCT04198064 - Pain Management for Cystoscopy: A Prospective Randomized Study Focused on Understanding the Role of the "Bag Squeeze" to Manage Pain for Patients Undergoing Cystoscopy N/A
Recruiting NCT05415865 - The Effect of Local Anesthetic Solution in the Bladder Prior to Botox Injections in the Bladder Phase 3
Completed NCT05374902 - Efficacy of Animation, Buzzy, and Multiple Interventions on Pain in Children N/A
Completed NCT04901611 - Parental Touch Trial (Petal) N/A
Completed NCT03768193 - Deep Serratus Anterior Plane Block vs Surgically-placed Paravertebral Block for VATS Surgery N/A
Recruiting NCT05267704 - Evaluating the Feasibility of VR for Pediatric Renal Biopsies N/A
Completed NCT04500158 - The Effect of Local Anesthesia on Control of Intraoperative Physiologic Parameters and Post Operative Comfort Phase 3
Recruiting NCT04718116 - Tapentadol Versus Tramadol Analgesia Post Cardiac Surgery N/A
Not yet recruiting NCT04610307 - EFFECT OF BUFFERED LOCAL ANESTHESIA ON PAIN IN ARETERIOVENOUS FISTULA N/A
Recruiting NCT06284473 - Ketamine as a Supplement to Local Anesthesia for Minor Procedures Phase 4
Completed NCT04203225 - Comparison of Two Application Techniques for LET Gel Phase 4
Not yet recruiting NCT06316934 - Lavender Aromatherapy to Decrease Anxiety/Pain Perception During Office Hysteroscopy Phase 2
Completed NCT05175924 - The Effect of Virtual Reality On Pain and Anxiety During Blood Draw in Children: A Randomized Controlled Study N/A
Completed NCT03004456 - Distraction for Reduction of Pain Associated With Venipuncture in the Pediatric Post-Transplant Population N/A
Completed NCT04762004 - Maternal Speech Decreases Pain Scores and Increases Oxytocin Levels in Preterm Infants During Painful Procedures N/A
Recruiting NCT05427903 - Two Approaches in Enhancing the Efficacy of Inferior Alveolar Nerve Block During Treatment of Mandibular First Permanent Molars With Symptomatic Irreversible Pulpitis N/A
Recruiting NCT05688670 - Regional Anesthesia Following Pediatric Cardiac Surgery Phase 4