Pain Perception Clinical Trial
Official title:
Acute Effects of High Intensity Interval Exercise on Executive Function
NCT number | NCT02270528 |
Other study ID # | HM20000451 |
Secondary ID | |
Status | Completed |
Phase | N/A |
First received | |
Last updated | |
Start date | October 2014 |
Est. completion date | July 2018 |
Verified date | August 2018 |
Source | Virginia Commonwealth University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study will examine the acute effects of high intensity interval ergometry on peripheral concentrations of lactate and hydrogen ions, as well as cognitive function. Approximately 60 healthy, college-aged males will participate in the Wisconsin Card Sorting Task (WCST), a measure of executive function, two times over a span of two weeks. Prior to the WCST, participants will complete either a warm-up, a warm-up and high intensity interval exercise, or a stationary period. Changes in lactate, pH, and WCST score will be evaluated between and within groups in relation to the presence of the high intensity exercise stimulus.
Status | Completed |
Enrollment | 16 |
Est. completion date | July 2018 |
Est. primary completion date | July 2018 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 18 Years to 35 Years |
Eligibility |
Inclusion Criteria: - Healthy male college students - Ages of 18-35 years old - Body fat percent < 25% Exclusion Criteria: - Moderate to high risk for cardiovascular disease - Reporting any known physical or psychological diseases or disorders - Participating in certain prescription and/or illegal drug use - Smoking - Body fat percent > 25% - Those having undergone any surgery, serious injury, or hospitalization within the past five years - Those having experienced a major life event (eg divorce, family death) in the past five years |
Country | Name | City | State |
---|---|---|---|
United States | Clinical Research Unit, MCVH-VCU | Richmond | Virginia |
Lead Sponsor | Collaborator |
---|---|
Virginia Commonwealth University |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Peripheral Blood Lactate | Lactate is known to increase during exercise. At each time frame, ~15mL of blood will be sampled from a subject via intravenous catheter. From this sample, blood will be analyzed for lactate using a YSI2300. | 8 times total; 2 at Baseline (Day 1; Minute 14 and Minute 29), 3 in session 1 (Day 3; Minute 2, Minute 18, and Minute 29), and 3 in session 2 (Day 17; Minute 2, Minute 18, and Minute 29); Maximum Time Frame at Session 2 (Day 17, Minute 29) | |
Primary | Peripheral Hydrogen Ions, Peripheral Blood pH | pH decreases during rigorous or intense exercise. At each time frame, ~15mL of blood will be sampled from a subject via intravenous catheter. From this sample, blood will be analyzed for Hydrogen Ions (pH) via a pH electrode. | 8 times total; 2 at Baseline (Day 1; Minute 14 and Minute 29), 3 in session 1 (Day 3; Minute 2, Minute 18, and Minute 29), and 3 in session 2 (Day 17; Minute 2, Minute 18, and Minute 29); Maximum Time Frame at Session 2 (Day 17, Minute 29) | |
Primary | Executive Function | Executive Function deals with the ability to problem solve, plan, and make decisions. The Wisconsin Card Sorting Task (WCST) is a computerized version of a task of executive function. Categories completed will be used as the measure of executive function ability. | 2 times total, 1 in session 1 (Day 3; Minute 20), 1 in session 2 (Day 17, Minute 20); Maximum Time Frame at Session 2 (Day 17, Minute 20) | |
Secondary | Ratings of Perceived Pain (RPP) | This is a visual analog scale used to determine an individual's relative perceived level of pain. The individual will mark on the scale how much pain they are experiencing. | 8 times total; 2 at Baseline (Day 1; Minute 15 and Minute 30), 3 in session 1 (Day 3; Minute 3, Minute 19, and Minute 30), and 3 in session 2 (Day 17; Minute 3, Minute 19, and Minute 30); Maximum Time Frame at Session 2 (Day 17, Minute 30) | |
Secondary | Ratings of Perceived Exertion (RPE) | RPE will be measured using Borg's scale of exertion. This is a numeric scale (6-20). An individual will state the number that correlates to the level of effort being given. | 8 times total; 2 at Baseline (Day 1; Minute 15 and Minute 30), 3 in session 1 (Day 3; Minute 3, Minute 19, and Minute 30), and 3 in session 2 (Day 17; Minute 3, Minute 19, and Minute 30); Maximum Time Frame at Session 2 (Day 17, Minute 30) | |
Secondary | Emotion (Feeling Scale, FS) | This is a numeric scale (-5 to +5). An individual will state the number that correlates to the emotion being felt (-5= Very Bad to +5+Very Good). | 8 times total; 2 at Baseline (Day 1; Minute 15 and Minute 30), 3 in session 1 (Day 3; Minute 3, Minute 19, and Minute 30), and 3 in session 2 (Day 17; Minute 3, Minute 19, and Minute 30); Maximum Time Frame at Session 2 (Day 17, Minute 30) |
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