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Comparison of Conventional Dose Regimen and New Dose Regimen of Pregabalin

Pain, Neuropathic Clinical Trial

Official title:
Comparison of Conventional Flexible Dose Regimen of Pregabalin and New Flexible Dose Regimen of Pregabalin Using Low Dose: A Randomized Controlled Trial

Clinical Trial Summary

The purpose of this study is to propose a new flexible dose regimen starting from 75mg using the low dose pregabalin 25 mg and 50 mg comparing the side effect and compliance with the conventional flexible dose regimen staring from 150mg using the pregabalin 75mg.

Clinical Trial Description

Pregabalin has been shown to be effective as a first-line medication for neuropathic pain but it appears to have several side effects such as dizziness, drowsiness, and edema, which lowers compliance with medications. A way to reduce side effects is the flexible dose regimen, which reaches the target dose to treat the drug. The proposed flexible dose regimen is a regimen that begins with twice the prevalence of 75 mg. However, dizziness is the most common side effect up to 20% in conventional flexible dose regimen. Therefore, the aim of this study was to propose a new flexible regimen starting at a dose less than the existing dose and to compare compliance with pregabaline according to both methods ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03691038
Study type Interventional
Source Kangbuk Samsung Hospital
Contact
Status Terminated
Phase N/A
Start date October 10, 2018
Completion date October 30, 2019
View Details
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