Impact of LPV During OFA on Postoperative Oxygen Saturation.

Status Not yet recruiting

Clinical Trial Summary

Observational study comparing patients with lung protective ventilation (LPV) following the consensus guidelines by Young C with patients getting routine lung ventilation, both during opioid free anesthesia (OFA).

Clinical Trial Description

The paper by C Young et al describes the essential steps in protecting the lungs and preventing post operative pulmonary complications (PPC) like alveolar collapse.

Alveolar collapse can be measured by oxygen saturation drop when no oxygen therapy is given, when full neuromuscular block (NMB) reversal and no opioid is given intra and postoperative.

LPV means:

tidal volume of 6 ml/kg, inspiratory-expiratory (I/E) ratio of 1/1, positive end expiratory pressure (PEEP) minimum 5 cmH20 and higher during laparoscopy in obese patients, Inspiratory oxygen concentration (FIO2) max 80% during induction and max 40 % during maintenance and extubation. Extubation in an awake, full NMB reversed patient getting no opioids while giving continuous positive airway pressure (CPAP) during withdrawal of the tube. Lung recruitment maneuver (LRM) when lung compliance decreases below 40 milliliter per centimeter water. (ml/cmH2O) ;

Study Design

Related Conditions & MeSH terms

Oxygen Saturation

Clinical Trial Details

NCT number	NCT04192305
Study type	Observational
Source	AZ Sint-Jan AV
Contact	Jan Paul Mulier
Phone	+32486729203
Email	jan.mulier@azsintjan.be
Status	Not yet recruiting
Phase
Start date	December 1, 2019
Completion date	December 2021

View Details

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