Overactive Bladder Clinical Trial
Official title:
Physical Therapy for Overactive Bladder
Verified date | November 2012 |
Source | National Taiwan University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | Taiwan: Department of Health |
Study type | Observational |
Overactive bladder is a syndrome of symptoms. The core symptom is urgency with/without urge
incontinence, frequency, nocturia. The prevalence of overactive bladder increased with age.
The elderly is increasing with time, so the people who suffering from overactive bladder is
also increasing. Research related to overactive bladder in the field of physical therapy is
remained needed. The purposes of this study are to investigate the application of physical
therapy to women with overactive bladder, emphasizing on the effect of voluntary muscle
contraction for urgency inhibition, including the urodynamic study and clinical study.
There are three stages in this study. In the first stage, we are going to develop a specific
health-related quality of life questionnaire for urinary incontinence in Taiwan version. One
hundred and fifty women with urinary incontinence and fifty healthy women without lower
urinary tract symptom will be recruited in the first year to investigate the reliability and
validity of the questionnaire. The Short-Form 36, Chinese version, will be used as gold
standard for validity. Fifty women with urgency will be recruited in the second stage to
test the effect of muscle active contraction strategies to inhibit detrusor pressure and
urgency. The three muscle active contraction strategies include pelvic floor muscle strong
contraction, pelvic floor muscle tonic contraction, and transversus abdominis tonic
contraction. The outcome variables including detrusor pressure of the urodynamic parameter
and self-reported urgency score. Simultaneous image record by abdominal ultrasound during
the urodynamic examination will be used to ensure the accuracy of muscle action. The
predictors of success of strategy from the result of the second year will be used to
stratify the patients in the third stage. Eighty women with urgency will be recruited in the
final stage to examine the clinical effect of strategy for urgency inhibition.
Status | Terminated |
Enrollment | 155 |
Est. completion date | October 2012 |
Est. primary completion date | June 2011 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 20 Years and older |
Eligibility |
Inclusion Criteria: - women with overactive bladder Exclusion Criteria: |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Taiwan | National Taiwan University Hospital | Taipei |
Lead Sponsor | Collaborator |
---|---|
National Taiwan University Hospital |
Taiwan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | urinary diary | 7 days | No |
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