Lutropin Alfa in Women at Risk of Poor Response

Status Completed

Clinical Trial Summary

Evaluate the effectiveness of adding lutropin alfa (recombinant human luteinizing hormone [r-hLH]) in the middle of the follicular phase compared to no addition, in infertile women at risk of poor response stimulated with follitropin alfa (recombinant Follicle-Stimulating Hormone [r-FSH]) under Gonadotropin Releasing Hormone (GnRH) antagonist in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI), in the number and quality of oocytes, follicular development, fertilization oocyte, embryo quality, and pregnancy rate.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Ovarian Stimulation

Clinical Trial Details

NCT number	NCT01112358
Study type	Interventional
Source	Merck KGaA
Contact
Status	Completed
Phase	Phase 2
Start date	December 7, 2005
Completion date	January 30, 2007

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See also
Status	Clinical Trial	Phase
Completed	`NCT01121991` - A Prospective Study to Evaluate the Addition of Subcutaneous Recombinant Human-Luteinizing Hormone With Recombinant Human-Follicle Stimulating Hormone on Follicular Development in Women Undergoing Ovarian Stimulation for Assisted Reproductive Technologies	Phase 3
Not yet recruiting	`NCT04539067` - Effect of Controlled Ovarian Stimulation in Quality of Oocyte and Embryo	Phase 2
Recruiting	`NCT02715336` - Efficacy and Safety of Medication Used to Stimulate Ovulation	Phase 4
Not yet recruiting	`NCT03298750` - Mechanical Stimulation of the Ovary for Infertility Treatment in Patients With Very Low Ovarian Reserve	N/A
Completed	`NCT03939403` - Conventional Ovarian Stimulation vs. Single Injection Stimulation of Corifollitropin Alfa in Oocyte Donor	Phase 4
Recruiting	`NCT06142708` - The Effect of Dual Trigger (GnRH Agonist + hCG) for Final Maturation in Oocyte Donors With History of a Previous Cycle With Suboptimal Response to GnRH Agonist Only Trigger	N/A
Recruiting	`NCT05166668` - Letrozole /GnRH Antagonist Protocol in Women Over 40 Years Undergoing ICSI Cycle	N/A
Completed	`NCT04549649` - The Effect of Dual Trigger for Final Oocyte Maturation on IVF/ICSI Outcomes in Patients With Suboptimal Ovarian Response	N/A
Terminated	`NCT01816789` - Age Versus Ovarian Reserve Markers Based Therapy in IVF (IVF)/Intracytoplasmic Sperm Injection (ICSI) Cycles	Phase 4
Completed	`NCT00823004` - Antagonist/Letrozole in Poor Responders	Phase 1/Phase 2
Not yet recruiting	`NCT06175832` - PPOS (Progestin Primed Ovarian Stimulation) and Corifollitropin Alfa (CFA) Cross-over Study	Phase 4
Completed	`NCT00830492` - Clomiphene Citrate (CC)/Gonadotropin/Gonadotropin Releasing Hormone (GnRH) Antagonist Versus Gonadotropin/GnRH Agonist	Phase 4
Completed	`NCT01145144` - Dehydroepiandrosterone Supplementation for Poor Responder Patients During in Vitro Fertilization Treatment	N/A
Completed	`NCT01037699` - Luteinizing Hormone (LH) Supplementation in Gonadotropin-releasing Hormone (GnRH) Antagonist Cycles	Phase 3
Completed	`NCT00829075` - Impact of Three Different Gonadotrophin Regimes on Egg Donation Program	Phase 4
Recruiting	`NCT03400722` - Double Ovarian Stimulation as Accumulation Strategy for Older Infertile Patients With Suboptimal Ovarian Response	Phase 4
Completed	`NCT00669786` - Human Menopausal Gonadotropin (HMG) vs Recombinant Follicle Stimulating Hormone (rFSH) in Gonadotropin Releasing Hormone (GnRH) Antagonist Cycles	Phase 3