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Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy

Ovarian Cancer Clinical Trial

Official title:
Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy

Clinical Trial Summary

The purpose of this research is to determine whether a 16-week virtually supervised aerobic and resistance exercise program is feasible in patients receiving first-line chemotherapy after surgery for ovarian or endometrial cancer and if it will improve lower extremity function (function of the legs), lessen chemotherapy-induced peripheral neuropathy (CIPN; numbness or tingling in the hands or feet), and if there is any effect on inflammatory blood markers (the level of a certain marker in the blood that is associated with inflammation; redness and swelling).

Clinical Trial Description

This research study is a randomized controlled trial that will compare an exercise group to a control group on lower extremity function, CIPN, and inflammatory markers in ovarian or endometrial cancer patients undergoing first-line chemotherapy after surgery. The names of the study interventions involved in this study are/is: - Aerobic and resistance exercise; virtually supervised 16-week aerobic and resistance exercise performed at home via Zoom - Attention control for 16 weeks, home-based stretching The research study procedures include: screening for eligibility and study interventions including evaluations and follow up visits. It is expected that about 30 people will take part in this research study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04997096
Study type Interventional
Source Dana-Farber Cancer Institute
Contact Christina Dieli-Conwright, PhD
Phone (617) 582-8321
Email ChristinaM_Dieli-Conwright@dfci.harvard.edu
Status Recruiting
Phase N/A
Start date April 2, 2022
Completion date April 30, 2025
View Details
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