A Study Evaluating MM-310 in Patients With Solid Tumors

Status Recruiting

Clinical Trial Summary

MM-310 is a liposomal formulation of a docetaxel prodrug that targets the EphA2 receptor on cancer cells. Docetaxel is an approved chemotherapeutic drug.This study is a Phase 1 open-label study of MM-310 in patients with solid tumors. In the first part of the study, MM-310 will be assessed as a monotherapy until a maximum tolerated dose (MTD) is established. After an MTD of MM-310 as a monotherapy is established, an expansion cohort and MM-310 in combination with other therapies will be assessed.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Adenocarcinoma
Carcinoma
Carcinoma, Non-Small-Cell Lung
Carcinoma, Squamous Cell
Carcinoma, Transitional Cell
Endometrial Carcinoma
Endometrial Neoplasms
Gastric Carcinoma
Head and Neck Neoplasms
Lung Neoplasms
Non-small Cell Lung Cancer
Ovarian Cancer
Ovarian Neoplasms
Pancreatic Ductal Adenocarcinoma
Prostate Adenocarcinoma
Prostatic Neoplasms
Sarcoma
Small Cell Lung Cancer
Small Cell Lung Carcinoma
Soft Tissue Sarcoma
Solid Tumors
Squamous Cell Carcinoma of the Head and Neck
Stomach Neoplasms
Triple Negative Breast Cancer
Triple Negative Breast Neoplasms
Urothelial Carcinoma

Clinical Trial Details

NCT number	NCT03076372
Study type	Interventional
Source	Merrimack Pharmaceuticals
Contact	Vasileios Askoxylakis, MD, PhD
Phone	617.441.7492
Email	VAskoxylakis@merrimack.com
Status	Recruiting
Phase	Phase 1
Start date	February 22, 2017
Completion date	December 2018

View Details

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