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NCT02719041 Clinical Trial

Predictive Biomarkers for IGF1R Targeted Therapy in Ovarian Cancer: a Retrospective Study

Ovarian Cancer Clinical Trial

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT02719041
Other study ID # HYMC-19-16
Secondary ID
Status Not yet recruiting
Phase N/A
First received March 13, 2016
Last updated March 20, 2016
Start date April 2016
Est. completion date April 2018

Study information
Verified date March 2016
Source Hillel Yaffe Medical Center
Contact Rinat Lift, MSc
Phone 972-4-6304335
Email rinatl@hy.health.gov.il
Is FDA regulated No
Health authority Israel: Ministry of Health
Study type Observational

Clinical Trial Summary

The main goal of this study is to employ a novel proteomic approach to identify predictive tumor biomarkers that will increase the efficacy of insulin-like growth factor (IGF1R) targeted therapy in epithelial ovarian cancer. It is expected that these predictive biomarkers will be applied to increase the response rate in selected groups of patients.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 40
Est. completion date April 2018
Est. primary completion date April 2018
Accepts healthy volunteers No
Gender Female
Age group 18 Years and older
Eligibility Inclusion Criteria:

- women who underwent surgery for ovarian cancer

Exclusion Criteria:

Study Design

Observational Model: Case-Only, Time Perspective: Retrospective

Related Conditions & MeSH terms

Intervention

Other:
• Immunohistochemistry staining method

Locations
Country Name City State
Israel Hillel Yaffe Medical Center Hadera

Sponsors (1)
Lead Sponsor Collaborator
Hillel Yaffe Medical Center

Country where clinical trial is conducted

Israel, 

Outcome
Type Measure Description Time frame Safety issue
Primary Responsive to IGF1R therapy Mean tumor volume will be calculated and growth inhibition will be reported as the percentage decrease of tumor volume compared with the control. One year No
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