Cardiac Catheterization in Cardiac Arrest

Status Not yet recruiting

Clinical Trial Summary

This is a pilot study that will lead to a large randomized control trial (RCT), to assess whether early versus late or no cardiac catheterization is associated with improved outcomes in out-of-hospital cardiac arrest (OHCA) patients.

Clinical Trial Description

A pilot multicenter RCT.

The objectives of the study are:

To assess whether early (within 12 hours) cardiac catheterization is associated with improved survival, neurologic and cardiovascular outcomes in OHCA patients.

Patients will be randomized 1:1 to early cardiac catheterization, performed as early as possible, within 12h post return of spontaneous circulation (ROSC) following OHCA, or to standard practice, which may include medical management without cardiac catheterization or late cardiac catheterization after completion of therapeutic hypothermia. Percutaneous coronary intervention (PCI) is recommended for culprit lesions found on diagnostic angiography. All patients will undergo therapeutic hypothermia started as soon as possible with target temperature below 36°C according to local practice. Other medical management will be according to standard of care ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02587494
Study type	Interventional
Source	Lawson Health Research Institute
Contact	Shahar Lavi, MD
Phone	519-6633611
Email	shahar.lavi@lhsc.on.ca
Status	Not yet recruiting
Phase	N/A
Start date	December 2017
Completion date	December 2018

View Details

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