Out-of-hospital Cardiac Arrest Clinical Trial
Official title:
Cognitive Impairment Following Cardiac Arrest and Target Temperature Management
This is a steering group approved substudy to the Target Temperature Management trial (TTM,
ClinicalTrials.gov Identifier: NCT01020916). TTM compares the effect of two strictly
controlled temperature regimes for survivors of out-of-hospital cardiac arrest.
The primary aim of this sub-study is to compare the amount of cognitive impairment in
cardiac arrest survivors treated with 33 degrees and 36 degrees and with a matched group of
control patients with myocardial infarction.
Our secondary aims are:
- To investigate the impact of cognitive impairment on our patients' ability to
participate in society and their health related quality of life.
- To investigate the relationship between our patients cognitive impairments and their
relatives/informants health related quality of life and feelings of burden.
- To test the hypothesis that the simple cognitive screening battery used in the TTM main
trial is sensitive enough to detect all patients with significant cognitive disability.
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Outcomes Assessor), Primary Purpose: Diagnostic
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