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Efficacy of Hyperbaric Oxygen Therapy in the Treatment of Osteoradionecrosis

Osteoradionecrosis Clinical Trial

Official title:
Efficacy of Adding Hyperbaric Oxygen Therapy to the Treatment of Late Radiation Damage of the Lower Jaw (Osteoradionecrosis).

Clinical Trial Summary

The purpose of this study is to determine whether hyperbaric oxygen therapy is effective in the treatment of osteoradionecrosis (late damage after radiotherapy) of the jaw.

Clinical Trial Description

Late radiation damage to the lower jaw (osteoradionecrosis (ORN)) is often seen in patients treated with radiotherapy for a tumor in the head and neck region. Part of the lower jaw becomes non-vital and has to be treated. ORN proofs to be a condition difficult to treat and the treatment for this condition varies.

In many countries hyperbaric oxygen therapy (HBOT) is added to the surgical treatment of ORN. Unfortunately there is no consensus whether the addition of hyperbaric oxygen therapy to the treatment of ORN is beneficial or not. This study has the aim to investigate the efficacy and cost-effectiveness of HBOT in the treatment of ORN ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00989820
Study type Interventional
Source Radboud University
Contact
Status Terminated
Phase Phase 2/Phase 3
Start date October 2009
Completion date May 1, 2018
View Details
See also
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