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PROs Following Low-dose Irradiation for Osteoarthritis — PRO-LO  

Osteoarthritis Clinical Trial

Official title:
Patient Reported Outcomes Following Low-dose Irradiation for Osteoarthritis (PRO-LO): A Single-arm Prospective Registry

Clinical Trial Summary

The goal of this observational registry study is to collect data related to patient reported outcomes (pain, function, quality of life, toxicity) in osteoarthritis (OA) patients receiving standard of care radiation therapy (RT).

Clinical Trial Description

This is a single-institution, single-arm, prospective, observational study of patients with osteoarthritis who are being treated with standard of care radiation therapy (RT). The purpose of this non-interventional study is to systematically collect data related to patient reported outcomes (pain, function, quality of life, toxicity) with the goal of optimizing approaches to management with radiation therapy and clinical care during follow up. The primary endpoint of this study is a change in visual analog pain scale (VAPS) at 3 months post radiation and a variety of secondary endpoints are aimed at assessing disease control, patient function, avoidance of invasive surgery, and toxicity. Participants will complete patient-reported outcome surveys for pain and joint-specific functional assessment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05705947
Study type Observational
Source University of North Carolina, Chapel Hill
Contact Victoria Xu
Phone 984-974-8744
Email victoria_xu@med.unc.edu
Status Recruiting
Phase
Start date May 31, 2023
Completion date May 2034
View Details
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