Osteoarthritis Clinical Trial
Official title:
Clinical Research on Intra-articular Injection of Human Autologous MSCs in Treatment of Knee OA
In this study, researchers want to determine the safety of MSCs that a patient can tolerate without causing side effects. Moreover researchers will also be looking at the function of the knee over time, which may give them some insight on the usefulness of MSCs as a treatment option.
Osteoarthritis (OA) is one of the most common forms of arthritis. It is a lasting condition
in which the material that cushions the joints, called cartilage, breaks down. This causes
the bones to rub against each other, causing inflammation, stiffness, pain and loss of joint
movement. Currently, there are few effective treatments available for patients suffering from
OA.
Mesenchymal stem cells (MSCs) are cells that have the ability to self-regenerate, which means
they have the ability to make copies of themselves and to turn into other kinds of cells
(e.g. cartilage cells). Stem cell science shows much promise for the future treatment of
osteoarthritis, but much of the research is still in the early stages. In this study,
researchers want to determine the safety of MSCs that a patient can tolerate without causing
side effects. Moreover researchers will also be looking at the function of the knee over
time, which may give them some insight on the usefulness of MSCs as a treatment option.
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