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Human Umbilical Cord Mesenchymal Stem Cell Transplantation in Articular Cartilage Defect

Osteoarthritis Clinical Trial

Official title:
Phase I Study of Human Umbilical Cord Mesenchymal Stem Cell Implantation in the Treatment of Articular Cartilage Defect of Knee

Clinical Trial Summary

The purpose of this study is to evaluate the safety and efficacy of human umbilical cord mesenchymal stem cell(hUC-MSC) for articular cartilage defect of knee.

Clinical Trial Description

Human articular cartilage has limited repair potential.Cell-based strategies have explored chondrocytes and mesenchymal stem cells (MSCs) with extensive basic science and preclinical studies.However the concept of autologous chondrocyte implantation is not ideal,so the focus in cartilage repair is shifting toward mesenchymal stem cells.

To investigate the effects of hUC-MSC treatment for articular cartilage defects, 20 patients will be enrolled and receive 4 times of hUC-MSC transplantation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02291926
Study type Interventional
Source Shenzhen Hornetcorn Bio-technology Company, LTD
Contact
Status Completed
Phase Phase 1
Start date December 2014
Completion date December 2016
View Details
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