Disability and Self-rated Health Following Primary Knee Replacement

Osteoarthritis Clinical Trial

Official title:

The Effects of Primary Knee Replacement for Osteoarthritis on Disability in Activities of Daily Living and Self-rated Health in Older People

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01236729
• Other study ID #: KL122009
• Status: Completed
• Start date: December 2009
• Est. completion date: December 31, 2015

Study information

• Verified date: October 2023
• Source: Coxa, Hospital for Joint Replacement
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Knee replacement is an effective treatment in late-stage osteoarthritis. It reduces pain and improves quality of life. There is, however, limited data concerning its results in older people and on its effect on how patients survive in regular activities of daily living (ADL), such as bathing and shopping. In this study, the results of knee replacement are evaluated from the point of view of disability in everyday activities and self-rated health. Moreover, association with ADL performance and clinical knee scores and severity of osteoarthritis are assessed.

Description:

This is a cross-sectional study with a 12 month follow-up for recruited patients. Most data are gathered by a postal questionnaire.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 460
• Est. completion date: December 31, 2015
• Est. primary completion date: November 30, 2013
• Accepts healthy volunteers: No
• Gender: All
• Age group: 75 Years and older

Eligibility

Inclusion Criteria:

• age 75 years or more at the time of operation

• diagnosis of knee osteoarthritis

• scheduled for or operated on with primary knee replacement

Exclusion Criteria:

• died during the follow-up

• inflammatory arthritides

Related Conditions & MeSH terms

• Knee Replacement
• Osteoarthritis

Locations

Country	Name	City	State
Finland	Coxa, Hospital for Joint Replacement	Tampere

Sponsors (2)

Lead Sponsor	Collaborator
Coxa, Hospital for Joint Replacement	Tampere University

Country where clinical trial is conducted

Finland, 

References & Publications (2)

Limnell K, Jamsen E, Huhtala H, Jantti P, Puolakka T, Jylha M. Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study. Aging Clin Exp Res. 2012 Dec;24(6):699-706. doi: 10.3275/8718. — View Citation

Vekama L, Puolakka T, Honkasalo M, Huhtala H, Moilanen T, Jamsen E. Functional gain following knee replacement in patients aged 75 and older: a prospective follow-up study. Aging Clin Exp Res. 2015 Dec;27(6):865-76. doi: 10.1007/s40520-015-0348-x. Epub 20 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Disability in activities of daily living		Baseline (recruitment) and at 12 months
Secondary	Overall self-rated health		Baseline (recruitment) and at 12 months
Secondary	Health-related quality of life (WOMAC)	For patients recruited in 2011-2012.	Baseline and 12 months postoperatively