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Osteoarthritis Pain clinical trials

View clinical trials related to Osteoarthritis Pain.

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NCT ID: NCT04296344 Completed - Clinical trials for Chronic Low Back Pain

Group Acupuncture Therapy With Modified Yoga

GAPYOGA
Start date: January 8, 2019
Phase: N/A
Study type: Interventional

Chronic pain is prevalent in the U.S., with impact on physical and psychological functioning as well as lost work productivity. Minority and lower socioeconomic populations have increased prevalence of chronic pain with less access to pain care and poorer outcomes. Acupuncture therapy is effective in treating chronic pain conditions including chronic low back pain (cLBP), neck pain, shoulder pain and knee pain from osteoarthritis (OA). Acupuncture therapy, including group acupuncture, is feasible and effective, and specifically so for underserved and diverse populations at risk for health outcome disparities. Acupuncture therapy also encourages patient engagement and activation. As chronic pain improves there is a natural progression to want and need to increase activity and movement recovery. Diverse movement approaches are important both for improving range of motion, maintaining gains, strengthening and promoting patient engagement and activation. Yoga therapy is an active therapy with proven benefit in musculoskeletal pain disorders and pain associated disability. The aim of this pilot feasibility trial is to test the bundling of these two care options for chronic pain, to inform both the design for a larger randomized pragmatic effectiveness trial as well as implementation strategies across underserved settings.

NCT ID: NCT01980940 Completed - Osteoarthritis Pain Clinical Trials

The Single Dose Pharmacokinetics of Two and Proof of Efficacy of One New Etoricoxib Gel Formulation in Participants With Osteoarthritis (MK-0663-168)

Start date: December 23, 2013
Phase: Phase 1/Phase 2
Study type: Interventional

Study Part 1 is designed to assess the plasma pharmacokinetics of etoricoxib (ETOR) 4% dimethyl sulfoxide (DMSO) and propylene glycol (PG) formulations, each at 2 different doses, upon single-dose topical administration on the knee of osteoarthritis participants. Study Part 2 is designed to evaluate the efficacy of topical etoricoxib vs. placebo in the treatment of osteoarthritis of the knee. The primary hypothesis is that topical etoricoxib will be more effective than placebo in the treatment of osteoarthritis of the knee over 2 weeks of treatment as assessed by time-weighted average change from baseline on the Western Ontario and McMaster Universities Arthritis Index (WOMAC) Visual Analogue (VA) 3.0 pain subscale.

NCT ID: NCT01780389 Completed - Osteoarthritis Pain Clinical Trials

Open-label Milnacipran for Persistent Knee Pain One Year After Total Knee Arthroplasty (TKA)

Start date: October 2010
Phase: Phase 4
Study type: Interventional

The current study examines the effects of milnacipran in patients who have chronic persistent knee pain one year or longer after total knee arthroplasty (TKA) to evaluate for a pain-relieving effect.

NCT ID: NCT01030640 Completed - Clinical trials for Chronic Low Back Pain

Study To Assess Changes In The Number Of Nerves In The Skin At The Site Where Where Tanezumab Is Injected

Start date: December 2009
Phase: Phase 1
Study type: Interventional

Subcutaneous administration of tanezumab can result in changes in the number of nerves around the injection site in the thigh.

NCT ID: NCT00917696 Completed - Osteoarthritis Pain Clinical Trials

Study to Evaluate ATP-induced Pain and ATP-induced Dermal Vasodilation by Iontophoresis (0000-118)(COMPLETED)

Start date: October 2009
Phase: Phase 1
Study type: Interventional

This study will evaluate ATP-induced Pain (AIP) and ATP-induced dermal vasodilation (AIDV) as target engagement tools for future development of analgesics.