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De-Escalation Radiotherapy in Patients With Low-Risk HPV-Related Oropharyngeal Squamous Cell Carcinoma — EVADER  

Oropharyngeal Cancer Clinical Trial

Official title:
A Phase II Single Arm Trial of Elective Volume Adjusted De-Escalation Radiotherapy (EVADER) in Patients With Low-Risk HPV-Related Oropharyngeal Squamous Cell Carcinoma

Clinical Trial Summary

The purpose of this study is to find out whether radiotherapy to some of the lymph node areas can be safely omitted to decrease side effects without increasing the risk of the tumour coming back.

Clinical Trial Description

The standard or usual treatment for this disease includes radiotherapy or radiotherapy combined with chemotherapy or antibody therapy. These treatments are highly effective at curing most patients with HPV-related cancer of the oropharynx, but short and long-term side effects from treatment can be significant. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03822897
Study type Interventional
Source Canadian Cancer Trials Group
Contact
Status Active, not recruiting
Phase Phase 2
Start date June 28, 2019
Completion date December 31, 2024
View Details
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